• Sorry Jenny that you have had such ‘side effects’.  As they say in Swahili ‘pole sana’ – a term of condolence that you may use in all circumstances from stubbing your toe to losing your mother-in-law.

    Not surprising to see such side effects considering the breadth of effects that the faulty Chloride transport in CF may be expected to have. Headaches and neurological signs may be expected as the Trikafta normalises electrolytes in the brain cells. Reducing the dose may be expected to reduce the progress . After a time on the lower dose you may be able to go up again with fewer side effects.

    Keep paddling!

     

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