Gene therapy using circular forms of DNA called plasmids may help treat lung disease in cystic fibrosis (CF), based on early lab studies, regardless of the disease-causing gene mutation, a study suggests. Optimized plasmids boosted production of the fully mature CFTR protein, which is missing or not working properly…
Discussion
During the summer of 2001, when my late daughter, Jasmine, was 9, she required a two-week hospital stay due to an acute pulmonary exacerbation — a complication of her cystic fibrosis (CF). Life was never the same after that. When I finally brought her home, the relief was…
Trikafta was associated with significant reductions in healthcare use, including hospitalizations related to cystic fibrosis (CF) complications affecting organs and systems outside the lungs, according to an insurance claims analysis. “Results of this study suggest a multisystemic benefit of [Trikafta] therapy with reductions in extrapulmonary…
In people with cystic fibrosis (CF), the timing of organ transplant — lung, liver, or both — relative to infection with the SARS-CoV-2 virus that causes COVID-19 did not affect the risk of severe outcomes, according to a large international study. Patients with poorer lung…
Discussion
Five years ago, I got the call. If you’re in the cystic fibrosis (CF) community and have had a double-lung transplant, you know the weight of those words. You know how the terror and the relief collapse into a single moment after you hang up the phone. You…
Discussion
Prior to my double-lung transplant eight years ago, I didn’t know anything about organ donation. While living with cystic fibrosis (CF), I hadn’t connected with others who had CF, either. I started to dip my toes in these spaces as I approached the transplant evaluation process, finding comfort in…
Among people with cystic fibrosis (CF), certain measures of blood vessel health — especially regarding the aorta, the body’s main artery — tend to vary according to biological sex, a new study reports. Researchers think these variations may help explain sex-specific differences in survival outcomes among people with CF,…
Becoming educated and informed about cystic fibrosis is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your CF journey.
There is no cure for CF yet, but here you can find more information about current therapeutic approaches, as well as experimental treatments that are in the pipeline.
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