Two drug developers are teaming up to advance toward clinical trials an inhaled treatment targeting the disease mechanisms underlying cystic fibrosis (CF). The U.S.-based Aptar Pharma and Aceso Therapeutics, headquartered in France, announced they will collaborate on developing ACT-101, an experimental RNA therapy. Unlike traditional drugs that target…

By the time my late daughter, Jasmine, turned 17, our days had settled into a kind of uneasy peace. The routines that helped us manage her cystic fibrosis (CF) had become second nature. Every morning began with the bronchial drainage machine thumping away in the living room as…

Children and adolescents with cystic fibrosis (CF) continue to experience mental health and behavioral concerns despite treatment with Trikafta (elexacaftor/tezacaftor/ivacaftor), according to a recent study. Caregiver anxiety and depression were also found to be associated with mental health and behavioral symptoms in their children, highlighting the importance of…

I took part in physical therapy (PT) on a weekly basis to build my strength during the lead-up to my double-lung transplant nine years ago. PT was mandatory to complete the prerequisite requirements to be listed for a transplant, but I learned so much about myself in ways that…

Higher than normal levels of several pH-regulating proteins can be found in the bronchial, or airway, cells of people with cystic fibrosis (CF), according to a new study. This suggests the body may be compensating for the loss of CFTR function — which helps regulate the movement of salt…

Life at home never really went back to normal after Jasmine’s last hospital stay. She was 16 and wise beyond her years in ways that only kids who’ve spent too much time in hospitals can be. Every day was a balancing act for me, between being her parent and being…