Cystic fibrosis (CF) carriers — and especially men with mutations in only one copy of CFTR, the gene associated with CF — are at a higher risk of developing a severe COVID-19 infection, one that carried a greater need for ventilation and could be quickly fatal, according to…

Here’s what you need to know about disabled people. First, don’t call them “disabled people” unless they want to be called disabled people. Or people with disabilities. Or neither. I don’t call myself a disabled person, personally. It’s not because I don’t support the community or consider myself an…

Health Canada has approved Trikafta  as a triple-combination therapy for people with cystic fibrosis (CF), ages 12 and up, who have at least one F508del mutation, the most common CF-causing mutation. This decision is expected to give about 1,100 people access for a first time to a therapy that directly…

A new strategy to correct so-called splicing mutations could help deliver nucleic acid therapies called oligonucleotides to cells in the lung, a new study suggests. This approach may aid in the development of new treatments for people with cystic fibrosis (CF), according to researchers. “With our oligonucleotide delivery platform,…

A mobile, dietary self-monitoring app used for six months to track food choices and manage pancreatic enzyme replacement therapy (PERT) helped children with cystic fibrosis (CF) to better meet disease-specific nutritional guidelines, a study shows. Still, the nutritional changes made were not sufficient to reach the standards of…