[beatrice-gallagher]

Hello, has anyone noticed their ALT and AST numbers rise? My grandson started Trikafta 2/2020 on 10/2020 his liver enzymes shot up. He is 20years old, we’re transitioning from pediatric doctors to adult specialist. His adult specialist noticed protein in his urine and as precaution set up CT scan’s and we found out not only does he have cirrhosis but also kidney stones. Two months ago after finding out I changed his high calorie diet to a much healthier one. I removed all the butter and breads and cut his salt intake. His AST is now normal 23 and his ALT has gone down to 66 from 147 in July 2022. I’m wondering if Trikafta has also corrected the malabsorption issue and the need for high calorie and salt intake? I’ve heard a few other people with CF now having high blood pressure with the extra salts that were told is needed. Anyone else notice besides the extra weight one is now gaining any other changes that now need to totally change the diet to a more lean and much less salt one? I’ve been raising him since he was 18 months, he’s autistic and when I found this site , I was happy that I found a place where I can ask other people about their experience’s with CF and especially Trikafta. 😊