Daniela Semedo, PhD,  —

Arch Biopartners Inc (Arch), recently announced that its drug candidate AB569, which is being developed as treatment for pulmonary Pseudomonas aeruginosa infections, has successfully concluded pre-clinical in vivo and in vitro validation trials. The news is significant to the CF community due to the prevalence of P. aeruginosa in those with…

ProQR Therapeutics, a Leiden, NL based biotech company focused on development of drugs to treat severe genetic disorders, recently announced that its PQ-010-002 clinical trial is open for patient enrollment. The study’s primary endpoint is the estimation of the effect of topical administration of QR-010 on the nasal mucosa…

In a special article published in the journal Mediators of Inflammation, a team of researchers led by Nades Palaniyar from the Lung Innate Immunity Research Laboratory at The Hospital for Sick Children Research Institute in Toronto, Canada reviewed the current research advances in the field of Cystic…

Children’s Healthcare of Atlanta, Emory University, and Georgia Tech were recently awarded a grant by The Cystic Fibrosis Foundation to expand the Atlanta CF Research and Development Program (CF@LANTA RDP Program). The four-year grant worth $1.8 million will enable the collaborating institutions to expand their current cystic fibrosis research projects and translate…

ManRos Therapeutics SA and Cyclacel Ltd, an exclusively owned subsidiary of Cyclacel Pharmaceuticals, Inc., recently announced a partnership, supply and licensing agreement for the commercialization and development of Cyclacel’s oral seliciclib capsules by ManRos for the treatment of patients with cystic fibrosis (CF). Under the terms…

ProQR Therapeutics N.V. a company developing RNA medicines for the treatment of severe diseases including cystic fibrosis, recently announced that it has initiated the enrollment of patients into PQ-010-001, a Phase 1b clinical trial for QR-010. The compound is a new RNA-based therapeutic drug designed to restore the genetic mutation in the mRNA…

Laurent Pharmaceuticals Inc., a Montréal-based private biopharmaceutical company currently developing a clinical stage lipid modulator (LAU-7b) designed to address the compromised immune-inflammatory response in Cystic Fibrosis (CF), recently announced positive data from its Phase 1b study that assessed LAU-7b in adult patients with CF. LAU-7b is a novel…

Galapagos NV, a clinical-stage biotechnology company, recently delivered a joint presentation with AbbVie during the 38th annual conference of the European Cystic Fibrosis Society held in Brussels, Belgium. The presentation revealed co-developed technologies to address CF, part of Galapagos’ pipeline that includes three Phase 2 programs, two Phase 1 trials, five pre-clinical studies, and…

Vertex Pharmaceuticals Incorporated  and Parion Sciences recently announced a joint collaboration for the development of investigational epithelial sodium channel (ENaC) inhibitors to treat cystic fibrosis (CF) and other pulmonary conditions. Based on the agreement rights, Vertex will develop and commercialize Parion’s ENaC inhibitors, named P-1037 and P-1055, for…

Denmark-based Serendex Pharmaceuticals, a company developing drugs to treat severe respiratory conditions, recently announced the initiation of a Phase I clinical trial for their drug candidate Molgradex, based on their Granulocyte Macrophage Colony Stimulating Factor (GM-CSF). The compound uses Novozymes‘ recombinant human albumin named Recombumin as an effective, versatile stabilizer that eases…