Airway epithelial cells carrying mutations that cause cystic fibrosis (CF) become more loosely connected when grown in the lab in the presence of insulin and high amounts of sugar, a study found, suggesting that CF-related diabetes may weaken the barrier that normally protects the airway tract. Researchers working at…
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Bonnie Ramsey, MD, a pediatrician and researcher who dedicated her career to advancing care for cystic fibrosis (CF), has been selected as the recipient of the 2025 American Pediatric Society (APS) John Howland Award. The APS has been giving this award since the early 1950s to recognize healthcare workers…
A Phase 1 trial that’s evaluating the safety and tolerability of an inhaled treatment called KIT2014 in healthy volunteers has started in Australia. KIT2014 is being developed by Kither Biotech as an add-on to existing CTFR modulators, to improve lung function and reduce inflammation in cystic fibrosis (CF)…
The cystic fibrosis (CF) treatment Trikafta leads to changes in airway cell gene expression, or activity, that may help fend off bacterial infections and lessen lung damage, researchers report. “This study identifies mechanisms through which ETI [Trikafta] is likely to improve antibacterial function, reduce lung damage, and reduce…
Becoming educated and informed about cystic fibrosis is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your CF journey.
There is no cure for CF yet, but here you can find more information about current therapeutic approaches, as well as experimental treatments that are in the pipeline.
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