News

November 25, 2020November 25, 2020

CFF Awards $3.3M to Advance Inhaled Antibiotic for Resistant P. aeruginosa Infections

cystic fibrosis, News

The Cystic Fibrosis Foundation (CFF) has awarded up to $3.3 million to Polyphor AG to advance the testing of an inhaled version of murepavadin, an antibiotic that targets multi-drug ... Read more

November 24, 2020November 24, 2020

CFF Awards Up to $3.75M to Develop Oral Antibiotic for NTM Infections

cystic fibrosis, News

The Cystic Fibrosis Foundation (CFF) awarded up to $3.75 million to Matinas BioPharma to support preclinical studies of MAT2501, a potential oral antibiotic to treat nontuberculous mycobacterium (NTM) infections in people ... Read more

November 23, 2020November 23, 2020

S. Aureus Found Mostly in Lung Mucus, Not Tissue, Pig Model Shows

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Using pig lungs as a model, scientists discovered that Staphylococcus aureus, a species of bacteria often found in the lungs of children with cystic fibrosis (CF), preferentially colonizes the mucus ... Read more

November 20, 2020November 20, 2020

CF Foundation Seeks Minority Patient Voices on Inequalities in Care, Research

News

In an effort to address racism within the cystic fibrosis (CF) community and the health disparities it fosters, the Cystic Fibrosis Foundation (CFF) is asking for greater input from people ... Read more

November 19, 2020November 19, 2020

Trial of MS1819, Pancreatic Enzyme Therapy, May Add New Patient Arm

cystic fibrosis, News

AzurRx BioPharma is requesting a new patient arm be added to its ongoing Phase 2b trial investigating MS1819 capsules as a treatment for exocrine pancreatic insufficiency (EPI) in people with cystic fibrosis (CF). ... Read more

November 18, 2020November 19, 2020

A. fumigatus Lung Infections Linked to Age, Long-term Antibiotic Use

cystic fibrosis, News

Adult age up to 50 and chronic antibiotic use seem to be the greatest risk factors for lung infection by the fungus Aspergillus fumigatus among cystic fibrosis (CF) patients, ... Read more

November 17, 2020November 17, 2020

Pegylation Provides Long‐acting Version of Dornase Alfa for CF Treatment

cystic fibrosis, News

A modified version of Pulmozyme (dornase alfa), a widely-used cystic fibrosis (CF) therapy, lasts longer and reduces the need for treatment from once a day to once a week, ... Read more

November 16, 2020November 16, 2020

Relizorb Use Supports Weight, Height Gains in Tube-fed Patients, Study Finds

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Relizorb, Alcresta Therapeutics‘ pancreatic enzyme treatment, led to significant weight and height improvements among cystic fibrosis (CF) patients with pancreatic insufficiency who require tube feeding, according to the results of ... Read more

November 13, 2020November 13, 2020

Trikafta Soon Be Up for Approval, Cystic Fibrosis Canada Reporting

cystic fibrosis, News

Following yearlong advocacy efforts, the triple-combination therapy Trikafta is expected to soon come up for approval before Health Canada, the country’s health regulatory agency, the non-profit patient group Cystic Fibrosis Canada has announced on its ... Read more

November 12, 2020November 12, 2020

KB407 Seen in Animal Studies to Safely Deliver Gene That Might Treat CF

cystic fibrosis, News

New findings from animal studies support the safety and effectiveness of KB407, a potential inhaled gene therapy for cystic fibrosis, its developer, Krystal Biotech, announced. Preclinical work is ongoing, and the therapy is ... Read more