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August 22, 2019August 22, 2019

Cellular Metabolism Defect May Cause Pseudomonas Lung Infections in CF Patients, Study Says

cystic fibrosis, News

A defect in cellular metabolism is the root cause for the high incidence of lung infections caused by the bacteria Pseudomonas aeruginosa in patients with cystic fibrosis (CF), a study ... Read more

August 21, 2019August 21, 2019

Trained Sniffer Dogs Can Detect Key CF Bacteria, Study Shows

cystic fibrosis, News

Trained sniffer dogs are able to detect Pseudomonas aeruginosa, the most common bacteria found in people with cystic fibrosis (CF), in liquid cultures even at very low concentrations, a ... Read more

August 20, 2019August 20, 2019

S. aureus Bacteria Seen to Lose Resistance to Antibiotics When Combined with Rhamnolipids

cystic fibrosis, News

Molecules used by a bacterial species against other microbes, called rhamnolipids, can bolster the ability of a standard antibiotic to penetrate treatment-resistant strains of Staphylococcus aureus by essentially making holes ... Read more

August 19, 2019August 19, 2019

Kalydeco Offers Better Quality of Life, Eased CF Symptoms, Patients Report

cystic fibrosis, News

Cystic fibrosis (CF) patients treated with Kalydeco (ivacaftor) who have the G551D mutation reported better health-related quality of life (HRQoL) and symptom relief than those on standard treatment who carry ... Read more

August 16, 2019August 16, 2019

High Liver Enzyme Levels Linked to Risk of CF-Related Diabetes, Especially in Men, Study Finds

cystic fibrosis, News

High blood levels of the enzyme alanine aminotransferase (ALT) — a biomarker of liver damage — might indicate a higher risk of rising blood sugar levels and cystic fibrosis-related diabetes ... Read more

August 15, 2019

Citing Costs, Scotland Regulators Reject Adding Orkambi and Symkevi to National Health System

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The Scottish Medicines Consortium (SMC) is recommending against bringing two of Vertex Pharmaceuticals’ approved cystic fibrosis (CF) treatments — Orkambi (lumacaftor/ivacaftor) and Symkevi (tezacaftor/ivacaftor) — into routine use by adding them ... Read more

August 14, 2019August 14, 2019

Lungs Grown in Yale Lab Have Potential for Patients with CF, Other Chronic Lung Diseases

cystic fibrosis, News

Lung transplants are the ultimate therapeutic strategy for many people with cystic fibrosis (CF) and other chronic lung diseases, but they are scarce due to the severe shortage of ... Read more

August 13, 2019August 13, 2019

Minimally Invasive Imaging Device Shows Changes in Nasal Airways, May Allow Earlier CF Diagnosis

cystic fibrosis, News

A minimally invasive imaging device that generates high-resolution images of nasal airways, including the cilia and mucus, allows researchers to visualize changes at the cellular level that underlie cystic ... Read more

August 9, 2019August 9, 2019

’65_RedRoses’ Event, Tracing Life of Woman with CF, Will Support Transplant Research in Canada

cystic fibrosis, News

A 10th anniversary screening of the documentary “65_RedRoses” will take place on Sunday, Sept. 8, at the Vancouver Playhouse Theatre to raise funds for the Transplant Research Foundation of ... Read more

August 8, 2019August 8, 2019

CF Foundation Earmarks Up to $15M for Arcturus Therapeutics to Advance Experimental RNA Therapy

cystic fibrosis, News

The Cystic Fibrosis Foundation (CFF) will give up to $15 million to Arcturus Therapeutics to advance the development of an experimental RNA therapy, called LUNAR-CF, to treat CF patients with all ... Read more

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