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January 17, 2019January 17, 2019

Phase 2 Trial Testing SPI-1005 for Ototoxicity in CF Patients Moving Forward

cystic fibrosis, News

Sound Pharmaceuticals (SPI) has enrolled its first-patient-in — meaning the first subject meeting the criteria for inclusion and exclusion of a clinical study — in a Phase 2 trial ... Read more

January 16, 2019January 16, 2019

CFF’s Preston Campbell: 2019 is a ‘Pivotal Year’ for CF Therapies

cystic fibrosis, News

A baby born with cystic fibrosis (CF) today can now expect to live a median 44 years, says Preston W. Campbell, MD, president and CEO of the Cystic Fibrosis ... Read more

January 15, 2019January 15, 2019

Immunotherapy May Be Promising Strategy to Treat Chronic Infections of P. aeruginosa in CF Patients

cystic fibrosis, News

Blocking the interaction between two molecules involved in immune restraining mechanisms — called PD-1 and PD-L1 — may be an effective therapeutic strategy to boost the immune system and ... Read more

January 14, 2019January 14, 2019

Eluforsen Improves CFTR Protein Function in CF Patients with F508del Mutations, Phase 1 Trial Shows

cystic fibrosis, News

An exploratory Phase 1 trial showed that repeated intranasal treatment with the therapy eluforsen improved CFTR protein activity in adults with cystic fibrosis (CF) carrying F508del mutations in both ... Read more

January 11, 2019January 11, 2019

WHO Approves Ensifentrine as Name for Potential Inhaled Treatment Now in Clinical Trials

cystic fibrosis, News

The World Health Organization (WHO) approved ensifentrine as the recommended name to identify the cystic fibrosis (CF) treatment candidate RPL554. Verona Pharma’s ensifentrine is an inhaled inhibitor of the enzymes phosphodiesterase ... Read more

January 10, 2019January 16, 2019

New Inhaled Carrier May Work for CF mRNA Therapy, Mouse Study Finds

cystic fibrosis, News

An inhaled form of messenger RNA (mRNA) with the potential to safely deliver therapeutics to the lungs of cystic fibrosis (CF) patients has been discovered by researchers at the ... Read more

January 8, 2019January 14, 2019

Vertex and Arbor Biotechnologies Collaborating to Develop Cystic Fibrosis Gene Therapies

cystic fibrosis, News

Vertex Pharmaceuticals and Arbor Biotechnologies have established a partnership to discover new proteins to advance the development of gene therapies for cystic fibrosis. The companies also plan to develop ... Read more

December 21, 2018January 10, 2019

Using Food as Medicine to Manage CF: A Nutritionist’s View

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As a clinician, I have consulted with many patients over the years and have had the opportunity to be inspired and impacted by many. Most recently I had the ... Read more

December 21, 2018December 21, 2018

AzurRx Starts Phase 2 Clinical Trial Testing MS1819-SD in CF Patients With EPI

cystic fibrosis, News

AzurRx BioPharma announced it has started a Phase 2 clinical trial testing the safety, tolerability, and efficacy of MS1819 Spray Dried (MS1819-SD) therapy in cystic fibrosis (CF) patients with ... Read more

December 20, 2018December 20, 2018

Gene Expression Patterns in Blood May Lead to Patient-tailored CF Treatment, Study Finds

cystic fibrosis, News

Researchers tested blood samples from cystic fibrosis (CF) patients and identified distinct gene expression patterns that could lead to patient-tailored treatments, a study reports. The study, “Identification of molecular ... Read more

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