News

SPLUNC1 may be marker of flares, treatment response in children

A protein secreted into the airways, called SPLUNC1, may be a sensitive biomarker of both mild pulmonary exacerbations and treatment response in children with cystic fibrosis (CF), a study suggested. Data showed that SPLUNC1 levels in patients’ sputum were low during an exacerbation, then significantly rose after oral and,…

Bacteroides gut bacteria may ease inflammation in CF lungs

Gut bacteria called Bacteroides had anti-inflammatory effects in the blood and airways of a mouse model of cystic fibrosis (CF) via its production of an immune-modulating metabolite called propionate, a study finds. The findings add to evidence of a so-called gut-lung axis, where microbes in the gut can influence…

Sweat study finds room for improvement in CFTR modulators

Some people with cystic fibrosis (CF) have levels of sweat chloride above the cut-off for a diagnosis of the disease despite being on CFTR modulators, suggesting there is room for improving treatment, a study found. The study, “Heterogeneity of CFTR modulator-induced sweat chloride concentrations in people with…

NY State chooses administrator for CF medical costs aid program

A New York State assistance program re-launched last year to provide financial aid to adults with cystic fibrosis (CF) for medical costs has a new administrator. The HealthWell Foundation‘s subsidiary HWF Direct has been tapped to administer the state’s Adult Cystic Fibrosis Assistance Program, known as ACFAP.