News

May 24, 2017May 24, 2017

Cystic Fibrosis May Interfere With Children’s Sleep, Study Reports

cystic fibrosis, News

Children with cystic fibrosis (CF) have less sleep and more sleep interruptions than healthy children, even when the disease is well-managed and stable, an Australian study indicates. The research, “How ... Read more

May 23, 2017May 23, 2017

40 Cystic Fibrosis Patients or Family Members Win Vertex’s First All in for CF Scholarships

cystic fibrosis, News

Forty cystic fibrosis patients or family members are winners of Vertex Pharmaceuticals‘ first All in for CF scholarships. The awards are for $5,000, making the total for the 2017-2018 academic year ... Read more

May 22, 2017May 22, 2017

Silent CFTR Mutation Has Negative Effect on Its Protein, After All

cystic fibrosis, News

So-called silent gene mutations in the cystic fibrosis (CF)-causing CFTR gene are not necessarily silent at all. A research team discovered that one such mutation also causes the resulting ... Read more

May 19, 2017May 19, 2017

Personal Spirometers May Help Pediatric CF Patients Improve Treatment Adherence, Study Suggests

cystic fibrosis, News

Abiding by the extensive treatment regimen for cystic fibrosis (CF) can be especially challenging for pediatric patients. A new study found that frequent monitoring of pulmonary function tests (PFTs) ... Read more

May 19, 2017May 19, 2017

Phase 2 Study of Oral Acebilustat in Treating Lung Inflammation Fully Enrolled in US, Europe

cystic fibrosis, News

Celtaxsys announced it has completed enrollment of its Phase 2b clinical trial evaluating the company’s lead anti-inflammatory candidate, oral acebilustat, in adult patients with cystic fibrosis (CF). Acebilustat (formerly known as ... Read more

May 18, 2017May 18, 2017

X-Chem, Vertex to Jointly Develop Small Molecules for CF, Other Severe Genetic Diseases

cystic fibrosis, News

X-Chem Pharmaceuticals and Vertex Pharmaceuticals will jointly develop small molecules targeting cystic fibrosis (CF) and other severe genetic diseases. Under the collaboration announced May 16, X-Chem will apply its proprietary DEX libraries — which ... Read more

May 18, 2017May 18, 2017

FDA, Using Precision Medicine, Triples Number of Cystic Fibrosis Mutations Kalydeco May Treat

cystic fibrosis, News

The U.S. Food and Drug Administration (FDA) has expanded its approval of Kalydeco (ivacaftor) to include cystic fibrosis (CF) patients with one of 23 additional rare mutations — more ... Read more

May 17, 2017May 17, 2017

Spyryx to Present Two Studies on SPX-101’s Ability to Treat Cystic Fibrosis by Clearing Airway Mucus

cystic fibrosis, News

Spyryx Biosciences will present two studies in Washington this week on SPX-101‘s ability to treat cystic fibrosis by clearing mucus from airways. One of the preclinical-trial studies it will discuss ... Read more

May 16, 2017May 16, 2017

Dalton, Arch Plan Joint Production of AB569 for Clinical Trials Involving Treatment-resistant Lung Infections

cystic fibrosis, News

Dalton and Arch Biopartners are partnering to manufacture AB569 for clinical trials involving cystic fibrosis (CF) patients with chronic, antibiotic-resistant bacterial lung infections. Under the agreement, the two will divide ... Read more

May 15, 2017May 18, 2017

Cypress-tree Substance Could Help Skirt Faulty Proteins in Cystric Fibrosis

cystic fibrosis, News

A substance found in a Japanese cypress tree can deliver iron to cells that are unable to obtain it because of faulty proteins, a finding that has implications for ... Read more