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Cystic Fibrosis (CF) is the most frequent, lethal genetic disorder, affecting roughly 30,000 people in the United States. Early death occurs mainly from chronic lung disease caused by persistent lower airway infection and inflammation. There are several important airway pathogens that are detrimental to CF patients, such as Staphylococcus…

The Food and Drug Administration (FDA) has given a Humanitarian Use Device approval to a novel device, the XPS™ and STEEN Solution™ XVIVO Perfusion System, which has the capacity to preserve donated lungs outside the human body for up to 4 hours before surgery into critically ill patients, including those…

Cystic Fibrosis is a serious genetic disease, with 1,000 new cases registered each year and more than 30,000 people affected in the US alone. Because the disease gradually debilitates lung function, it increases the probabilities of developing a lung infection, causing a major impact on a patient’s quality of…

Biopharmaceutical company AbbVie and the non-profit organization Cystic Fibrosis Research, Inc. (CFRI) recently announced a new partnership at the 27th National Family Cystic Fibrosis Education Conference (August 1-3.) The partnership will highlight the CF Chef program, which will help raise both funding and awareness on the…

The majority of patients suffering from cystic fibrosis (between 80-90% of the patient population) are affected by exocrine pancreatic insufficiency (EPI), a condition usually present at birth and commonly diagnosed within their first year of life. However, a new experimental therapy for the condition has shown to be…

With more than half of the patients with cystic fibrosis developing diabetes and most of them exhibiting insulin insufficiency, researchers at the Chinese University of Hong Kong conducted a study to explain this relationship and suggest a potential treatment strategy for CF-related Diabetes. The study, published this month in…

A team of researchers from the University of Pittsburgh has discovered that people with unexplained pancreatic problems might have a previously unknown type of cystic fibrosis that doesn’t affect the lungs. According to the Cystic Fibrosis Foundation, there are over 30,000 children and adults in the United…

Sick children under 12 years old needing a lung transplant, and who were previously almost totally dependent on lung donations from other children, can now have broader access to donated organs from adults, thanks to a new decision from the Organ Procurement and Transplantation Network (OPTN). Adolescent donation protocol will…

Following the recent success of a phase 3b clinical trial for Aztreonam in cystic fibrosis (CF) patients with Burkholderia infections, Gilead Sciences, Inc., a research-based biopharmaceutical company engaged in CF drug discovery and development, completed another phase 3 clinical trial to evaluate the safety of inhalable Aztreonam (AZLI)…

A recent study led by GBI Research entitled “Cystic Fibrosis Therapeutics in Major Developed Markets 2019 – CFTR Modulators Initiate Drive Towards Personalized Treatment and Market Growth,” notes that the Cystic Fibrosis market will grow from $695.6 million in 2012 to near a $ 4.5 billion in 2019 in…