Ana Pena, PhD,  —

The active ingredient of Synspira’s SNSP113, an inhaled investigational treatment for chronic lung infections, demonstrated an ability to completely eliminate antibiotic-resistant Pseudomonas aeruginosa bacteria, a major cause of lung disease in…

Disease severity in cystic fibrosis (CF) may be associated with an overreaction of the immune system to the fungus Aspergillus fumigatus, particularly due to a type of white blood cell called a phagocyte — which ingests and kills invading organisms — a study suggests.  U.K.

A new population of lung stem cells capable of repairing the airways following a severe injury was identified in two preclinical studies. These cells’ ability to transform and replace several lung cell types may be explored for regenerative medicines to treat diseases such as cystic fibrosis.

Celtaxsys has obtained four U.S. patents, including a new one for acebilustat, its lead candidate for treating the lung inflammation found in cystic fibrosis. The other three patents cover potential therapies for additional inflammatory diseases. Acebilustat is designed to reduce an overabundance of white blood cells known as neutrophils in CF…

A single dose of inhaled hypertonic saline (HS) solution increases mucus clearance for at least four hours in adults with cystic fibrosis (CF), concludes researchers at the University of North Carolina and John Hopkins University. Their study, “Hypertonic saline has a prolonged effect on mucociliary clearance in adults with cystic…