Daniela Semedo, PhD,  —

 KaloBios Pharmaceuticals, Inc. recently announced data on a Phase 2 randomized double-blind, placebo-controlled trial of KB001-A, an anti-PcrV monoclonal antibody (mAb) fragment, to be used as treatment for Pseudomonas aeruginosa (Pa) lung infections in subjects with cystic fibrosis (CF). The KB001-A trial enrolled 182 patients with CF who had their lungs…

A new study entitled “Pulsed direct and constant direct currents in the pilocarpine iontophoresis sweat chloride test,” recently published in the journal BMC Pulmonary Medicine, compared the production and volume of sweat, side effects caused by pulsed direct current, and constant direct current, and sought to determin the…

Galapagos is a company specializing in novel mechanisms of small-molecule and antibody programs for cystic fibrosis.  In a recent press release, the company revealed that before the end of 2015, they are going to conduct a Phase 1 clinical trial of a new corrector called GLPG2222 in conjunction…

A new study  from a team of researchers of the University of Pittsburgh Center for Vaccine Research (CVR), entitled “Engineered Cationic Antimicrobial Peptides (eCAPs) to Overcome Multidrug Resistance by ESKAPE Pathogens” demonstrated the effectiveness of new antibiotic agents as inhibitors of the growth of drug-resistant bacteria. The findings…

A new study published in the Orphanet Journal of Rare Diseases, presented the effectiveness of Cysteamine for the treatment of Cystic Fibrosis. The study, entitled  “Cysteamine (Lynovex®), a novel mucoactive antimicrobial & antibiofilm agent for the treatment of cystic fibrosis” was conducted by NovaBiotics Ltd.  researchers. Cystic…

In the United Kingdom, The Cystic Fibrosis Trust along with the children’s charity Action Medical Research, are funding a laboratory test of an inhaled treatment targeting lung dehydration in Cystic Fibrosis. Cystic fibrosis (CF) is a condition that usually affects children and young people and includes symptoms such…