Daniela Semedo, PhD,  —

Galapagos NV and AbbVie recently expanded their collaborative agreement in cystic fibrosis (CF) to mirror the successful growth of their CF portfolio, with an ultimate goal of developing a triple combination therapy able to treat 90 percent of all cystic fibrosis patients. Triple combinations of CF compounds already in the companies’…

The Cystic Fibrosis Foundation announced that it welcomes the recent creation of a Cystic Fibrosis Caucus in the U.S. Senate, several years after a similar caucus was established in the lower branch of the U.S. Congress, the House of Representatives. The foundation also thanked the bipartisan work of two…

AmpliPhi Biosciences, a biotech company focused on the development and commercialization of novel bacteriophage-based antibacterial therapeutics, recently presented new data at the European Congress of Clinical Microbiology and Infectious Diseases about the in vitro and in vivo activity of its investigational phage mix AB-PA01. Chronic lung infections caused by Pseudomonas aeruginosa are a major…

TGV-Inhalonix announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug designation to its antimicrobial agent as a possible treatment for antibiotic-resistant bacterial lung infections in patients with cystic fibrosis (CF). Mul-1867 is a nebulized solution designed for easy self-administration. According to the company, it is the first inhaled antimicrobial being developed…

Raptor Pharmaceutical Corp. announced that the first commercial sales of Quinsair (levofloxacin inhalation solution), a treatment for adults with cystic fibrosis, have been made in Denmark and Germany. Quinsair is an antibiotic for the twice-daily treatment of long-term lung infection caused by the bacteria Pseudomonas aeruginosa in adults with cystic fibrosis (CF). P. aeruginosa is…

Over 500 members and volunteers of the Cystic Fibrosis Foundation were present at the recent 2016 Volunteer Leadership Conference, a two-day event honoring those whose efforts have made a difference in the lives of people with cystic fibrosis. Joe O’Donnell was the recipient of the Dream Big Award, in recognition of his…

Early nutritional intervention and monitoring for respiratory and gastrointestinal disease in the youngest cystic fibrosis (CF) patients is vital to improving long-term outcomes. Clinical care guidelines specific to infants with CF, and nutrition and pulmonary guidelines for children over 6 years of age exist, and published by the CF Foundation. However,…

Personalized medicine, providing treatments tailored to individual factors down to the molecular level, is a promising approach for a highly variable disease like cystic fibrosis (CF). The approach is particularly important for children with CF, a group at particular risk of health complications that last for decades. CF, an inherited disease, is well-positioned to…

Laurent Pharmaceuticals, Inc., recently announced the completion of a financing round, led by the Cystic Fibrosis Canada, to support a Phase 2 clinical trial of LAU-7b in patients with cystic fibrosis (CF) that is expected to begin this year in the U.S. and Canada. “We are pleased to support Laurent Pharmaceuticals in its effort…

The U.S. Food and Drug Administration has granted Qualified Infectious Disease Product (QIDP) designation to MP-376, Raptor Pharmaceutical’s inhaled levofloxacin to treat pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis; non-cystic fibrosis bronchiectasis (BE); and nontuberculous mycobacteria (NTM). Raptor, based in Novato, California, is a global biopharma that’s focused on…