Marisa Wexler, MS,  senior science writer—

Treating expectant mothers with CFTR modulators may help to reduce the risk of intestinal complications for babies with cystic fibrosis (CF), according to a small real-world study from France. “We hope that such a study, merged with other international programmes, will also provide support for the European Medicines…

Undergraduate and graduate students in the U.S. who have cystic fibrosis (CF) are invited to apply for Abbvie‘s CF Scholarship program — the 2025 applications are now open, according to the pharmaceutical company’s website. Each year, the program selects 40 students for awards, with each given a…

The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to RCT2100, an experimental treatment for cystic fibrosis (CF) that’s currently in early clinical testing for patients who do not respond to or do not tolerate CFTR modulator therapies. The designation is meant to give extra…

The Cystic Fibrosis Foundation is once again accepting applications for its Impact Grants, a funding initiative that offers $10,000 per year for up to two years to support programs that empower people living with cystic fibrosis (CF). Applications can be submitted via an online portal and…

Biomx has raised $12 million in financing to advance BX004, a phage therapy being developed to treat bacterial infections — specifically, ones caused by Pseudomonas aeruginosa, known as P. aeruginosa for short — in people with cystic fibrosis (CF). The funding comes from investors purchasing the company’s stock,…

A European Medicines Agency (EMA) committee recommended that the label for Kaftrio be expanded to cover treatment for people with cystic fibrosis (CF) caused by a wider array of mutations, Kaftrio’s developer Vertex Pharmaceuticals said. The Committee for Medicinal Products for Human Use (CHMP) opinion will be reviewed…

Boehringer Ingelheim has launched a Phase 1/2 clinical trial of BI 3720931, an inhaled gene therapy designed to treat cystic fibrosis (CF). The first-in-human trial, dubbed LENTICLAIR 1 (NCT06515002), is expected to enroll about 36 adults with CF who are not eligible for treatment with CFTR…

Young children with cystic fibrosis (CF) have less mature gut bacterial growth over time than do their typically developing peers, according to a new U.S. study. “Our findings demonstrate that the gut microbiota of infants with CF fails to undergo typical developmental maturation, instead remaining entrenched in a transitional-like…

In cystic fibrosis (CF), certain immune cells show signs of dysfunction very early in life, according to a new study that used an animal model as well as blood samples from young children with CF. Researchers think immune cell deficiencies may influence the cycles of infection and inflammation that…

Registration is now open for BreatheCon 2025, an annual online event hosted by the Cystic Fibrosis Foundation that aims to foster connections between adults with cystic fibrosis (CF). This year’s BreatheCon will take place Feb. 7-8. Registration and additional information about the virtual event is available on the…