Patricia Inácio, PhD,  science writer—

About 10% of adolescents and young adults with cystic fibrosis (CF) have abnormal eating patterns, according to a single-center study. Results suggested that nutrition-focused subscales of the Cystic Fibrosis Questionnaire-Revised (CFQ-R), a tool commonly used for assessing health-related quality of life in CF, may help identify young patients at risk…

A six-week treatment with Kaftrio led to marked improvement in exercise capacity in adolescents with cystic fibrosis (CF), according to an analysis of three cases. The study, “Elexacaftor–Tezacaftor–Ivacaftor improves exercise capacity in adolescents with cystic fibrosis,” was published in the journal Pediatric Pulmology. CF is caused by mutations in…

Most adults with cystic fibrosis (CF) report experiences with painful or frightening medical procedures in childhood after their diagnosis, according to a U.K. study. These patients may benefit from psychosocial support from CF teams, who can ask about trauma in childhood in a safe and sensitive manner, researchers say.

Two patients have been dosed in a clinical trial testing BX004, a nebulized phage therapy designed to kill Pseudomonas aeruginosa, the most common cause of lung infections in people with cystic fibrosis (CF). The Phase 1b/2a trial (NCT05010577), which is funded by the Cystic Fibrosis Foundation and underway in…

A pediatric gastroenterologist in Missouri has been awarded a $50,000 grant to open a study into the potential of an FDA-approved nonsurgical device, called IB-Stim, as a way of easing abdominal pain in children with cystic fibrosis (CF). The grant, by the Institute of…

Problems with the CFTR protein — which causes cystic fibrosis (CF) — limit the replication and spread of SARS-CoV-2, the virus that causes COVID-19, in cells of the lung’s airways to protect patients, a study suggests. Cells lacking the CFTR gene responsible for that protein…

In children with cystic fibrosis (CF) and a first or new-onset Pseudomonas aeruginosa infection, antibiotics given intravenously are not more effective at eliminating the bacteria than inhaled antibiotics given alone or as combination therapy, a Turkish study suggests.  Intravenous (IV) treatment was also associated with more pulmonary exacerbations and poorer lung function after…

Elevated levels of DMBT1 in the lungs, a protein previously linked with inflammatory processes, may be a biomarker of progression in cystic fibrosis (CF) patients, a study suggests. High DMBT1 levels impaired the movement of cilia, the finger-like projections that help to clear mucus from the airways, its scientists…

American Airlines and its partners recently raised $1.2 million to support the Cystic Fibrosis Foundation during its 37th annual American Airlines Celebrity Ski event. In 37 years the event has raised more than $44 million supporting research to find a cure for CF. “For nearly 40 years, American Airlines…

The U.K. Cystic Fibrosis Trust has launched the CFTruths campaign, which is designed to enhance public awareness and understanding of cystic fibrosis (CF) and how patients routinely take precautions that now are associated mainly with preventing COVID-19. CFTruths comes on the heels of a YouGov poll organized by the Trust,…