Patricia Inácio, PhD, science writer —

A pediatric gastroenterologist in Missouri has been awarded a $50,000 grant to open a study into the potential of an FDA-approved nonsurgical device, called IB-Stim, as a way of easing abdominal pain in children with cystic fibrosis (CF). The grant, by the Institute of…

Problems with the CFTR protein — which causes cystic fibrosis (CF) — limit the replication and spread of SARS-CoV-2, the virus that causes COVID-19, in cells of the lung’s airways to protect patients, a study suggests. Cells lacking the CFTR gene responsible for that protein…

In children with cystic fibrosis (CF) and a first or new-onset Pseudomonas aeruginosa infection, antibiotics given intravenously are not more effective at eliminating the bacteria than inhaled antibiotics given alone or as combination therapy, a Turkish study suggests.  Intravenous (IV) treatment was also associated with more pulmonary exacerbations and poorer lung function after…

Elevated levels of DMBT1 in the lungs, a protein previously linked with inflammatory processes, may be a biomarker of progression in cystic fibrosis (CF) patients, a study suggests. High DMBT1 levels impaired the movement of cilia, the finger-like projections that help to clear mucus from the airways, its scientists…

American Airlines and its partners recently raised $1.2 million to support the Cystic Fibrosis Foundation during its 37th annual American Airlines Celebrity Ski event. In 37 years the event has raised more than $44 million supporting research to find a cure for CF. “For nearly 40 years, American Airlines…

The U.K. Cystic Fibrosis Trust has launched the CFTruths campaign, which is designed to enhance public awareness and understanding of cystic fibrosis (CF) and how patients routinely take precautions that now are associated mainly with preventing COVID-19. CFTruths comes on the heels of a YouGov poll organized by the Trust,…

Treatment with Trikafta is linked with fewer infection-related hospitalizations and a reduced need for antibiotics among people with cystic fibrosis, a study based on real-world U.S. data indicated. The study, “The rapid reduction of infection-related visits and antibiotic use among people with cystic fibrosis…

Worldwide, only 12% of people with cystic fibrosis (CF) have access to the triple combination therapy Trikafta, despite this next-generation medicine being suited to a “large proportion” of patients, a study on global rates of CF diagnosis and treatment reported. Global estimates of total CF patients are also likely underestimated due…

Adults and children with cystic fibrosis (CF) experienced a marked increase in food insecurity — meaning a limited or uncertain availability of foods that are nutritionally adequate and safe  — during the COVID-19 pandemic, a U.S. study found. Patients with food insecurity also reported poorer mental health and self-care…

Exon skipping may be a promising approach for cystic fibrosis (CF) patients carrying nonsense mutations in the CFTR gene, which render current CF therapies less effective, a study reported. Researchers were able to raise CFTR protein function and protein response to approved CF therapies in cells isolated from a patient…