Patrícia Silva, PhD, director of science content —

Galapagos NV announced the start of its SAPHIRA Phase 2 exploratory study with the first dosing of GLPG1837 in a cystic fibrosis (CF) patient. Topline results are expected in late 2016. CF is triggered by a mutation in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein, resulting in abnormal…

Alegeus recently announced that it will donate a total of $20,000 to three charities — including the Cystic Fibrosis Foundation — as part of its 2015 holiday giving program. Instead of handing out corporate gifts and holiday cards, Alegeus opted to let employees chose charities to support. Votes given to the three…

Proteostasis Therapeutics, Inc., announced that it recently received Fast Track Designation from the U.S. Food and Drug Administration (FDA) for PTI-428, an investigational oral treatment for cystic fibrosis (CF). CF is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, resulting in a disruption of ion…

Three Case Western Reserve University faculty members recently received significant funding from the National Center for Accelerated Innovation (NCAI) to conduct projects and develop novel technologies targeting sickle cell anemia, malaria, and cystic fibrosis (CF). NCAI supports new technologies and innovative products that have been targeted as…

The Geisel School of Medicine at Dartmouth announced that it has received a $10 million gift from an anonymous donor, plus a $5 million matching donation, also given anonymously, that will be used to accelerate its research into better treatments and, ultimately, a cure for cystic fibrosis (CF). The $15 million in…

Nivalis Therapeutics announced that the U.S. Food and Drug Administration (FDA) has granted its lead investigational drug, N91115, orphan drug status for the treatment of cystic fibrosis (CF). Drug candidate N91115 is a stabilizer of the CF transmembrane conductance regulator (CFTR) protein. Orphan drugs are generally those with a limited…

University of New Mexico researcher Graham Timmins has developed a diagnostic breath test, known as the urease test, that has the potential to rapidly confirm diseases like tuberculosis (TB) by detecting bacterial enzymes (ureases) in the lungs. The test was developed for TB, but Dr. Timmins plans to investigate its efficacy in other lung…

Cystic Fibrosis News Today has covered news of the latest treatments, events, clinical trials, and research updates in cystic fibrosis on a daily basis throughout the past year. As 2015 comes to an end, here are 10 articles most widely read by Cystic Fibrosis News Today readers, each with a brief summary of the developments that…

A Case Western Reserve University researcher is starting two studies, based on angiotensin signaling and gene “correction,” to advance research into more effective ways of treating cystic fibrosis (CF) and to better understand the ideal timing for such interventions. Both studies will begin in January. CF is due to a defective gene that causes a thick buildup…

Ryan Kelly has been named the 17th football player to win the 2015 Rimington Trophy. The award, which was announced last Thursday on December 10 according to a recent press release, is given annually to the Most Outstanding Center in NCAA Division I-A College Football in the U.S., and is determined by a consensus of All-American…