Patricia Valerio, PhD,  —

Secondhand, or passive, exposure to tobacco smoke led to an additional mean loss of 5% predicted lung function in young cystic fibrosis (CF) patients than in those who were unexposed, a review study shows. Researchers analyzed the results of six studies, which used a clinical test known…

A year of insulin treatment improves nutritional status and respiratory function in cystic fibrosis (CF) patients with diabetes, according to a study in Italy. In addition, CF patients treated with insulin at an early stage of abnormal blood sugar levels have reduced hospital admissions due to…

Defects in both epithelial and immune cells contribute to changes in the gut microbiota, the populations of microbes naturally present in the gut, seen in cystic fibrosis (CF), a recent study in mice showed. While the immune component had the greater effect in the small intestine, however, the epithelial…

Blood levels of two hormones, kisspeptin and proopiomelanocortin, are lower in people with cystic fibrosis (CF) — beginning in childhood and continuing through adulthood — than in healthy people, a study found. These reduced concentrations may be associated with lower body weight, delayed puberty and poorer fertility in CF…

Twelve months into the COVID-19 pandemic, Australian adults and children with cystic fibrosis (CF) showed improved lung function and body mass index (BMI), as well as a lower hospitalization rate, a study reports. “Differing models of care and major changes in community interactions both have the…

First Wave BioPharma is teaming up with Rho for a Phase 2 clinical trial to test their new adrulipase formulation, designed as a treatment for exocrine pancreatic insufficiency (EPI) in people with cystic fibrosis (CF). “We are eager to…

Researchers in Oregon have developed lipid nanoparticles that can be inhaled and effectively deliver messenger ribonucleic acid (mRNA) into the lungs of mice, triggering the cells to produce the defective protein in cystic fibrosis (CF). “Inhaled [lipid nanoparticles] resulted in localized protein production in the mouse lung without toxicity,…