Steve Bryson, PhD, science writer —

A more rapid decline in lung function in people with cystic fibrosis (CF) has been linked in a new study to high sputum levels of a virus that infects the bacteria Pseudomonas aeruginosa, which is a major contributor to lung disease in CF. The virus, called Pseudomonas filamentous…

Although parents of children with cystic fibrosis (CF) recognize the benefits of their children getting physical activity in schools, they see certain barriers in the school setting as preventing daily exercise for their children. Teachers’ misconceptions about CF, a failure to prioritize physical activity, and the physical limitations of…

Chronic infection with the hepatitis E virus (HEV) may be linked to pig-derived pancreatic enzyme replacement therapy (PERT) in people with cystic fibrosis (CF) who underwent lung transplants, a study found. CF patients in general had disproportionately higher rates of antibodies against HEV, regardless of transplant status, and…

People with cystic fibrosis (CF) experience a more severe disease course when they continue to have a small hole between the heart’s upper chambers that fails to close naturally after birth, a study suggests. The hole, called patent foramen ovale (PFO), in CF patients was linked to more…

More gastroenterologists with expertise in cystic fibrosis (CF) are needed alongside registered dietitians to provide comprehensive patient care, a survey study has found. The survey of registered dietitians and gastroenterologists found the involvement of gastroenterologists in caring for CF patients varied widely across specialty centers, with barriers that included…

The immune system of people with cystic fibrosis (CF) might be impaired due to long-term persistent lung infections and inflammation, a study suggested. Using a new and noninvasive standardized test for immune function called TruCulture, scientists found a lesser release of certain immune signaling proteins in immune cells from…

The balance of acids and bases in the urine of people with cystic fibrosis (CF) reflects lung and pancreas function, and the response to treatment, a study finds. The findings support measuring the bicarbonate base in urine, which mirrors the levels of various acids, as a tool to clinically…

A Phase 1b study that’s evaluating the safety of RCT2100, ReCode Therapeutics‘ investigational genetic medicine for people with cystic fibrosis (CF), has dosed its first patient. The inhalation therapy is being developed for CF patients who don’t respond to CFTR modulator therapies. “The initiation of our Phase…

The Cystic Fibrosis Foundation has awarded $3 million to support a study of mental health among young children with cystic fibrosis (CF) to University at Buffalo (UB) researcher Beth A. Smith, MD, a psychiatrist whose work in this area has already helped to get new screening programs into…

An infant boy, who was first seen with recurrent infections and a failure to thrive, was diagnosed with cystic fibrosis (CF) caused by a rare genetic mutation, a case study reports. “This case underscores the importance of considering CF even when classic symptoms are absent, as genetic mutation can…