Author Archives: Steve Bryson PhD

Aerosolized Therapy Restores CFTR in Patient-derived Cells

ReCode Therapeutics’ investigational aerosolized RNA-based therapies for cystic fibrosis (CF) restored CFTR function, the defective protein in CF, in patient-derived lung cells. Delivered by the company’s selective organ targeting (SORT) lipid nanoparticle (LNP) platform, the therapy showed no signs of toxicity in epithelial cells that line the airways.

Some Severe Asthma Patients Carry CFTR Variants: Genetic Study

Some people with severe asthma, an inflammatory lung condition, carry variants of the CFTR gene that causes cystic fibrosis (CF), a genetic study found. These findings support the genetic assessment of severe asthma patients with CF-related symptoms, the scientists recommended. The study, “DNA Sequencing Analysis of…

Exercise, Like CF Services Moved Online With Pandemic: UK Survey

The COVID-19 pandemic markedly limited exercise training and related services provided at cystic fibrosis (CF) care centers in the U.K., but they largely continued through online offerings, a survey found. Most clinics adapted by expanding telehealth services to include online exercise classes, clinical monitoring, and consultations, responses showed, and many…