News

Investigational treatment Encala (Lym-X-Sorb) is safe, well tolerated, and increased dietary fat absorption in patients with cystic fibrosis (CF) and pancreatic insufficiency, according to an analysis from a Phase 2 clinical trial. Findings from the analysis were reported in the study, “Improved residual fat malabsorption…

A deputy sheriff’s squad car, lights ablaze and sirens blaring, recently raced to Benjamin Clackum’s house on a sleepy residential street in Lawrenceville, Georgia, but no one was getting arrested. In fact, it was quite the opposite. Clackum was being presented with an AffloVest, a device that would make…

During COVID-19, the U.K. Cystic Fibrosis Registry is taking steps to further the collection of data on how the ongoing pandemic is affecting people with cystic fibrosis (CF). The CF Registry, managed by the Cystic Fibrosis Trust, records data on patients in England, Wales, Scotland, and Northern…

Pravibismane suspension, a new type of inhaled antimicrobial medication developed by Microbion, has received orphan drug designation from the U.S. Food and Drug Administration…

MyCyFAPP, a mobile app designed to help patients with cystic fibrosis (CF) manage their pancreatic enzyme replacement therapy (PERT) regimen, can improve the quality of life of children with the disease, particularly those with severe gastrointestinal (GI) symptoms, study says. The study, “Use…

Kalydeco treatment led to fewer deaths, transplants, hospitalizations, and exacerbations in people with cystic fibrosis (CF) compared to patients who did not receive the therapy, according to a five-year, real-world analysis of patient registries in the U.S. and U.K.  The results of…

People with cystic fibrosis (CF) have higher levels of DNA from common microbes that cause CF-related infections circulating in their blood compared to healthy controls, a study discovered. These findings support the development of a simple blood test as a noninvasive…

The nonprofit group OneLegacy has launched a video series, available on its social media channels, to raise awareness of the importance of organ and tissue donations. Called “Sound Good?” the four-part series features the stories of two teenagers and high school friends, one who is struggling with heart disease and…

In addition to restoring CFTR protein function in cells, the cystic fibrosis (CF) therapies Orkambi (lumacaftor/ivacaftor) and Symdeko (tezacaftor/ivacaftor combo) significantly reduce the excessive inflammation that damages patients’ lungs, a recent study suggests. Symdeko seems to be more potent than Orkambi at dampening inflammatory responses.

Oxford Hospitals Charity has purchased and delivered machines able to measure lung function at home to 120 young patients with cystic fibrosis (CF) in the U.K., enabling them to closely monitor their condition during the COVID-19 pandemic. The mini lung function machines were funded with the…