News

TORPEDO-CF Clinical Trial Seeks Participants for Antibiotic Study

Patients living with cystic fibrosis (CF) are at increased risk for acquiring and developing severe respiratory infections. The most worrisome pathogen is Pseudomonas aeruginosa (PsA), which is treated with powerful antibiotics either via oral, intravenous, or inhaled antibiotics. While these treatments are known to work, there has yet to be a conclusive…

La Jolla Pharmaceutical Acquires Rights to Gentamicin Derivatives for CF, Other Genetic Diseases

La Jolla Pharmaceutical Company has just announced it has entered two exclusive licensing agreements with the Indiana University Research and Technology Corporation (IURTC), and the IURTC and the University of Alabama at Birmingham (UAB). The agreements cover intellectual property rights for the company’s next-gen gentamicin derivatives, LJPC-30Sa and LJPC-30Sb, as antimicrobial agents…

Medication-Blocking Mucus Barrier in Lungs Breached Using Nanoparticles

The first nanotechnology-enabled gene delivery system capable of efficiently penetrating the hard-to-breach mucus barrier shielding human airway and lung tissue may have been discovered with potential to one day develop an inhaled vehicle for delivery of targeted therapeutic genes that may be delivered directly to the lungs at levels sufficient…

Newly Discovered Gene Therapy Could Help Treat Cystic Fibrosis

An increasing number of studies testing gene therapies are showing promise for treating a wide range of conditions, including cystic fibrosis. Normally in these studies, genes are injected into cells using a virus, however, scientists recently tested a new method of delivering DNA to the faulty CFTR gene in CF through what is called a cationic liposome, a fatty container…