A new study revealed that the cystic fibrosis transmembrane conductance regulator (CFTR) plays an important role in regulating the intestinal inflammatory responses. The study, entitled “CFTR Knockdown induces pro inflammatory changes in intestinal epithelial cells,” was published in the Journal of Inflammation…
News
Scientists at the Center for Nanomedicine at the Wilmer Eye Institute, part of Johns Hopkins University School of Medicine, may have found a new way to track the stages and the progression of cystic fibrosis (CF) by examining mucus in the lungs of CF patients. If so, mucus under a microscope…
A researcher from the Faculty of Medicine, Shiraz University of Medical Sciences, in Iran, has suggested the unconventional idea that people with cystic fibrosis (CF) could be more resilient to cholera and, vice versa, that people who contract cholera could develop resistance to cystic fibrosis. The work, titled “Cystic…
Assistant Professor Sigrid Ladores, PhD, from the School of Nursing, University of Alabama at Birmingham, and doctoral student Leigh Ann Bray are developing a study entitled “Female Fertility in the Age of New CFTR-Modulating Drugs.” The main focus of the research study will be to assess female patients’ understanding of…
A new study revealed that treating P. aeruginosa biofilms with the antibiotic tobramycin together with mannitol — two well-known therapies in treating lung infections in CF — did not reduce overall bacterial load. The study entitled “Mannitol Does Not Enhance Tobramycin Killing of Pseudomonas aeruginosa in a Cystic Fibrosis Model System…
The Strategies to Realize Innovation, Vision and Empowerment (STRIVE) Awards, which are granted by PTC Therapeutics, Inc., will now include a focus on cystic fibrosis (CF) advocacy as well. The company recently announced the extension of the STRIVE program and that it will begin offering funding to nonprofit organizations focused on the…
OrPro Therapeutics, Inc. has announced it has been granted a patent by the US Patent and Trademark Office (USPTO) for its lead candidate Theradux™, covering its unique treatment ability for cystic fibrosis (CF). The company has been developing a treatment pipeline based on thioredoxin, a naturally secreted protein with enzymatic activity known to have…
Vertex Pharmaceuticals, Inc. and CRISPR Therapeutics have announced that they will collaborate on drug research and development using CRISPR’s proprietary gene editing technology CRISPR-Cas9 to discover novel, potential treatments that address the underlying genetic causes of diseases such as cystic fibrosis (CF). The collaboration between Vertex and CRISPR will evaluate the use…
The burden of cystic fibrosis (CF) is both physical and psychological for those with the disease — a struggle that many people are unaware of. Photographer Ian Pettigrew recently published the book Salty Girls to capture CF patients’ everyday reality and to celebrate the women who suffer…
Persons with Cystic Fibrosis (CF) between ages 11 and 25 who think they can help inspire and engage other young people living with CF are being invited to check out a new program from the U.K.’s Cystic Fibrosis Trust. The Trust is reaching out to young people living with CF…
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