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Different CF Potentiators Bind to Same Flexible Spot on CFTR Protein, Study Finds
Approved and investigative cystic fibrosis (CF) treatments known as CFTR potentiators work by binding to the same flexible protein spot — a place that acts like a hinge — and keeping it open, according to a study whose findings may lead to more effective therapies.
The research, “Structural identification of a hotspot on CFTR for potentiation,” was published in the journal Science. Read a summary of this research here.
What do you think of this study and its findings?
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