Posts by: Alice Melão

cystic fibrosis, News

The University of North Carolina (UNC) is among only a few institutions in the United States that offers patients with inflamed pancreas (pancreatitis) or pancreatic cystosis a surgical treatment option ... Read more

June 12, 2018June 12, 2018

#ECFS2018 – Preclinical Data Shows Potential of ELX-02 to Reverse Effects of CFTR Nonsense Mutations

cystic fibrosis, News

Preclinical studies show that Eloxx Pharmaceuticals’ lead therapy candidate ELX-02 can reverse the effects of CFTR gene nonsense mutations in mice and cystic fibrosis (CF) patient-derived organoids. These findings ... Read more

June 11, 2018June 11, 2018

#ECFS2018 – AB-PA01, with Antibiotics, Shows Promise in Treating Drug-resistant Lung Infections in CF

cystic fibrosis, News

AmpliPhi Biosciences’ investigative therapy AB-PA01, in combination with antibiotics, shows significant potential to treat multi-drug resistant Pseudomonas aeruginosa infection in cystic fibrosis (CF), according to the case report of a CF patient ... Read more

June 11, 2018June 11, 2018

#ECFS2018 – Inhaled Mannitol Helps to Improve Lung Function in Adults with CF, Phase 3 Trial Data Show

cystic fibrosis

Treatment with inhaled mannitol is safe and can help to improve lung function in adult patients with cystic fibrosis (CF), a post hoc analysis of data from a concluded ... Read more

June 8, 2018June 8, 2018

#ECFS2018 – ARRIVAL Trial Shows Kalydeco to Improve Outcomes in Toddlers, Other Studies Support Real-life Benefits

cystic fibrosis, News

Results of the Phase 3 ARRIVAL study show that Kalydeco (ivacaftor) has the potential to modify the course of toddlers with cystic fibrosis. The trial’s most recent finding were ... Read more

June 8, 2018June 8, 2018

#ECFS2018 – Tobacco Smoke Exposure Greatly Speeds Loss of Lung Function in Children with CF, Study Reports

cystic fibrosis, News

Exposure to tobacco smoke is a key contributor to worsening lung function in young children with cystic fibrosis (CF), researchers report in a study that highlights both the importance ... Read more

June 7, 2018June 7, 2018

#ECFS2018 — Next-Generation CFTR Correctors for Cystic Fibrosis Show Promise in Early Trial Data

cystic fibrosis, News

Preliminary clinical trial data of three investigational next-generation CFTR correctors, being developed by Vertex Pharmaceuticals, provides the first demonstration of their potential to improve the outcome of cystic fibrosis ... Read more

June 6, 2018June 6, 2018

#ECFS2018 – HOPE-1 Trial Shows Potential of SPX-101 to Improve Lung Function in CF Patients

cystic fibrosis, News

Results of a Phase 2 trial showed that treatment with Spyryx’s investigative drug SPX-101 can improve lung function in patients with cystic fibrosis, regardless of their background genetic mutation ... Read more

June 4, 2018June 4, 2018

#ECFS2018 – Proteostasis Therapeutics Provides Update on CF Clinical Development Program

cystic fibrosis, News

Proteostasis Therapeutics will present an update on its cystic fibrosis (CF) clinical programs — which include an amplifier, a corrector, and a potentiator of the CFTR gene — at the upcoming 41st European Cystic Fibrosis ... Read more

May 31, 2018May 31, 2018

Way Found to Use Antimicrobial Peptides, Part of Immune System, to Treat Bacterial Lung and Wound Infections

cystic fibrosis, News

Antimicrobial peptides administered as tiny nanoparticles show promise in treating bacterial infections without risking making the bacteria more resistant to treatment — as can happen with antibiotics, an EU-supported ... Read more

Posts by: Alice Melão

Alice Melão

Pancreatic Cell Transplant Program Offers New Hope to Some CF Patients

#ECFS2018 – Preclinical Data Shows Potential of ELX-02 to Reverse Effects of CFTR Nonsense Mutations

#ECFS2018 – AB-PA01, with Antibiotics, Shows Promise in Treating Drug-resistant Lung Infections in CF

#ECFS2018 – Inhaled Mannitol Helps to Improve Lung Function in Adults with CF, Phase 3 Trial Data Show

#ECFS2018 – ARRIVAL Trial Shows Kalydeco to Improve Outcomes in Toddlers, Other Studies Support Real-life Benefits

#ECFS2018 – Tobacco Smoke Exposure Greatly Speeds Loss of Lung Function in Children with CF, Study Reports

#ECFS2018 — Next-Generation CFTR Correctors for Cystic Fibrosis Show Promise in Early Trial Data

#ECFS2018 – HOPE-1 Trial Shows Potential of SPX-101 to Improve Lung Function in CF Patients

#ECFS2018 – Proteostasis Therapeutics Provides Update on CF Clinical Development Program

Way Found to Use Antimicrobial Peptides, Part of Immune System, to Treat Bacterial Lung and Wound Infections

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