Andrea Lobo, PhD,  science writer—

A report described episodes of skin rash associated with joint pain and inflammation, known as dermatitis-arthritis syndrome, in four females with cystic fibrosis (CF). The patients had similar symptoms, including pink, swollen, itching skin eruptions associated with joint pain. The researchers proposed cystic fibrosis dermatitis arthritis syndrome as a…

A researcher at the University of California, Los Angeles (UCLA) has been awarded the Elizabeth Nash Postdoctoral Fellowship to develop a targeted cystic fibrosis (CF) gene therapy delivery system, the university announced. The two-year, $65,000-per-year fellowship, awarded annually by the Cystic Fibrosis Research Institute to support new…

Treatment with Trikafta (elexacaftor/tezacaftor/ivacaftor) may ease anxiety and depression symptoms in adults with cystic fibrosis (CF), a study found. A higher proportion of patients experienced a clinically significant easing in both anxiety and depression symptoms than those who saw their symptoms worsen. Those with clinically significant changes in…

Most infants with cystic fibrosis (CF) must be fed fortified milk, that is, breast milk, formula, or a combination of both, within the first six months of life to achieve normal growth by age 3, a study suggests. This lets babies receive all the benefits from breast milk, plus…

About one-quarter of men with cystic fibrosis (CF) have low testosterone levels, according to a new study that sought to assess the prevalence of this sexual health issue in males with the genetic disease. Neither age nor the time of day when testosterone measurements were taken influenced the levels…

Treatment with Kalydeco (ivacaftor) for almost eight years consistently improved lung function and reduced mortality in people with cystic fibrosis (CF), according to a study looking at several measures of disease progression. The therapy also significantly improved nutritional status, which together with reduced pulmonary exacerbations, hospitalizations, and lung…

In a real-world study involving children with cystic fibrosis (CF) in Italy, Kaftrio — an approved CF therapy sold as Trikafta in North America — was shown to lead to significant improvements in lung function for more…

Danish children with cystic fibrosis (CF) born between 2000 and 2022 showed noticeable gains in growth during their first five years of life, with those born after 2016 seeing the most progress in reaching normal growth standards, a study shows. This is likely due to newborn screening programs (NBS)…

Levels of fat-soluble vitamins D and E and of the micronutrients zinc and selenium are generally within the normal range in people with cystic fibrosis (CF), even during treatment with Kaftrio. That’s according to a recent study that also found significantly increased vitamin A levels one year into…

Extended treatment with Kaftrio progressively increases the diversity of the microorganisms in the gut in people with cystic fibrosis (CF), a recent study suggests. However, gut microbiota diversity remained significantly different from healthy people after about 1.5 years on the CFTR modulator, probably due to the use…