Joana Carvalho, PhD, managing science editor —

Treatment with ABBV-2222, an investigational CFTR corrector formerly known as GLPG2222, was well-tolerated and partially corrected the function of the CFTR protein, both alone and in combination with Kalydeco (ivacaftor), in a group of patients with cystic fibrosis (CF), Phase 2 clinical trials show. Trial findings…

AzurRx BioPharma has reached its patient enrollment goal in the ongoing Phase 2 trial testing the effectiveness of MS1819-SD, the company’s investigational therapy for the treatment of patients with exocrine pancreatic insufficiency (EPI) associated with cystic fibrosis (CF). MS1819-SD is a recombinant (artificial) form of an enzyme…

Abeona Therapeutics‘ new gene therapy ABO-401 for the treatment of cystic fibrosis (CF) has successfully delivered a functional version of the CFTR gene to the lungs of mice with CF, according to a preclinical study. In addition, the therapy showed the potential to restore the function of CFTR protein…

Motif Bio has entered an agreement with Lamellar Biomedical to undertake a preclinical study that will test a new therapeutic combination for treating lung infections in patients with cystic fibrosis (CF). Under the terms of the agreement, Motif Bio will launch a preclinical study to assess the effectiveness…

Students with cystic fibrosis have the opportunity to apply for up to $25,000 in scholarships under the AbbVie CF Scholarship program for the 2019-2020 academic school year, AbbVie announced. The program is intended for U.S. students with cystic fibrosis (CF) pursuing an undergraduate or graduate degree at an accredited institution.

People with cystic fibrosis (CF) who have been infected by cytomegalovirus (CMV) are more likely to experience faster disease progression and reach end-stage lung disease compared to those who have not been infected, a study shows. Findings of the study, “Cytomegalovirus…

Choline supplementation improves lung function and liver health in people with cystic fibrosis (CF), and should be considered as a complementary treatment to current standard care therapies, a study suggests. The findings of the study, “Choline Supplementation in Cystic Fibrosis — The Metabolic and Clinical Impact,”…

Despite being commonly found in patients with cystic fibrosis-related diabetes, the bacteria Stenotrophomonas maltophilia cannot be considered as an independent risk factor for developing CFRD, study says. The study, “Cystic fibrosis related diabetes is not independently associated with increased Stenotrophomonas maltophilia infection: Longitudinal data from the UK CF Registry,”…

The nutritional status of cystic fibrosis (CF) patients after a lung transplant — as assessed by body composition — is a strong predictor of lung function post-surgery, a study shows. The study, “Impact of nutritional status on pulmonary function after lung transplantation for cystic fibrosis,” was published in the…