Author Archives: Joana Fernandes, PhD

#NACFC2016 – Potential Treatments for Biofilm Infections and Intestinal Inflammation Show Promise in Early Studies

Promising results of preclinical studies evaluating the effectiveness of SYGN113 to treat bacterial biofilms in the lungs of patients with cystic fibrosis (CF), and of SYGN303 to treat the gastrointestinal consequences of the disease, were presented at the North American Cystic Fibrosis Conference (NACFC) now taking place in Orlando. Bacterial biofilms are…

Treating Fungal Infection in Cystic Fibrosis Patients Can Harm Lungs, Study Reports

Treating patients with cystic fibrosis (CF) or chronic obstructive pulmonary disease (COPD), infected with the fungus Aspergillus fumigatus, with antifungal therapies may contribute to the adaptation and resistance of this microorganism, and exacerbate lung infection, a new study reported. This finding, in a report by medical researchers in the Netherlands, underscores the…

CF Gender Gap May Be Caused by Estrogen-Protein Conflict

A new study published in the journal Science Advances sheds light on the molecular mechanisms responsible for the pathology of cystic fibrosis (CF), and may assist in the development of targeted therapies against the disease. Researchers investigated the role of two proteins, KCNE3 and KCNQ1, and how they can contribute…