A recent Dutch study found preoperative infection or inflammation to be associated with worse outcomes in cystic fibrosis (CF) patients undergoing lung transplantation surgery. This finding might help clinicians better estimate risk before such surgery. The study, titled “Pretransplant HRCT Characteristics Are Associated with Worse Outcome of Lung Transplantation for Cystic Fibrosis Patients,“…
A new study published in the journal e-LIFE has taken a novel approach to looking at deficits in protein folding associated with mutations in the CF transmembrane conductance regulator (CFTR) gene, the underlying cause of cystic fibrosis (CF). By identifying the signaling networks controlling protein folding, the study opens…
A new study in The Journal of Molecular Diagnostics found that the genetic screening panel for cystic fibrosis (CF) — based on a list of 23 known mutations — is not adequate for diagnosing nonwhite populations. CF is caused by mutations in the transmembrane conductance regulator (CFTR)…
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