Airway epithelial cells carrying mutations that cause cystic fibrosis (CF) become more loosely connected when grown in the lab…
Articles by Margarida Maia, PhD
Bacterial ecotin has the potential to reduce lung damage in cystic fibrosis (CF) by inhibiting the activity of an…
Cells from the lungs of people with cystic fibrosis (CF) are less susceptible to infection by SARS-CoV-2, the COVID-19-causing…
Mucus-producing cells in people with cystic fibrosis (CF) have lower levels of ST3Gal1, an enzyme that sugarcoats mucus to…
Gene therapy was found to work as well as a combination of the three CFTR modulators in Trikafta to…
While physical health and life quality gains can be evident in people using CFTR modulators, a group of disease-modifying…
The first healthy volunteers have been dosed in Australia as part of two separate Phase 1 clinical trials of SION-719…
Mice mimicking cystic fibrosis (CF) have trouble forming and taking up fat droplets, which limits normal growth and optimal…
Sionna Therapeutics has gained the rights to develop and market three of AbbVie’s clinical-stage compounds, a move that…
Despite treatment with Kalydeco (ivacaftor), females with cystic fibrosis (CF) continue to experience more lung exacerbations — periods…