Margarida Maia, PhD, science writer —

Margarida is a biochemist (University of Porto, Portugal) with a PhD in biomedical sciences (VIB and KULeuven, Belgium). Her main interest is science communication. She is also passionate about design and the dialogue between art and science.

Articles by Margarida Maia

Molecular Glue May Help CFTR Protein Work Better

A type of ring-shaped molecule called a macrocycle can help CFTR — the faulty protein in cystic fibrosis (CF) — go to the cell’s membrane, where it exerts its action, and work better in lab-grown cells carrying the most common CF-causing mutation, a study showed. These benefits were associated…

Kaftrio May Ease CF Symptoms of Acid Reflux, Sinonasal Infection

Kaftrio, a triple combination of elexacaftor, tezacaftor, and ivacaftor sold as Trikafta in the U.S., may ease acid reflux and symptoms of nasal and sinus cavity infection in cystic fibrosis (CF) patients with advanced lung disease, a U.K.-based study found. The study, “Elexacaftor-tezacaftor-ivacaftor improve gastro-oesophageal reflux and…

Use of CFTR Modulators May Protect Against Severe COVID-19

Taking so-called CFTR modulators — medications to correct the disease-causing faulty CFTR protein in cystic fibrosis (CF) — may significantly reduce a patient’s risk of severe COVID-19, according to a study by an international team of researchers. In fact, non-lung transplant CF patients in the U.S. and the U.K. using…

CF-370 Reduces Hard-to-treat Bacteria in Rabbit Model

CF-370, an expeimental therapy by ContraFect, reduces the number of hard-to-treat Pseudomonas aeruginosa bacteria in a rabbit model of pneumonia, an infection that inflames the lungs. P. aeruginosa, the most common cause of lung infections in people with cystic fibrosis (CF), can evade the body’s immune…

Inflamed Esophagus Cause of Oral Aversion for 3 Children With CF

Difficulties with eating and proper nutrition for cystic fibrosis (CF) patients may be due to an inflammation of the esophagus known as eosinophilic esophagitis (EoE), according to a report on three young children in the U.S. Shared traits, particularly gastrointestinal issues like gastroesophageal reflux disease (GERD) and abdominal pain that leave children…

Telerehabilitation May Help Children Feel Less Anxious

Telerehabilitation — the delivery of rehabilitation care from a distance using technology — may make children with cystic fibrosis (CF) feel less anxious or depressed, have a more positive body image, and also improve their ability to walk farther, a small study found. However, the levels of anxiety and…