SPL84-23, an investigational antisense oligonucleotide (ASO), restored the levels and function of CFTR — the defective protein in cystic…
Articles by Marta Figueiredo, PhD
Yap and Taz — two proteins involved in lung injury responses and regeneration — suppress the maturation of mucus-producing goblet…
During adolescence and young adulthood, healthy siblings of cystic fibrosis (CF) patients have to find ways to achieve a…
Cystic fibrosis (CF) patients with lower aerobic exercise capacity — assessed with a non-invasive cardiopulmonary exercise test — have…
Kalydeco (ivacaftor) safely and effectively improved lung function, growth, and nutrition in children and adults with cystic fibrosis…
Cystic fibrosis (CF) carriers — and especially men with mutations in only one copy of CFTR, the gene associated…
A mobile, dietary self-monitoring app used for six months to track food choices and manage pancreatic enzyme replacement therapy…
RCT223 and RTX0001, ReCode Therapeutics’ experimental RNA-based therapies for cystic fibrosis (CF), safely restored function to CFTR, the…
Lower levels of certain volatile molecules in the breath of children and adults with cystic fibrosis (CF) can distinguish with…
The therapeutic benefits of the triple-combination medication Trikafta are mostly due to the effects of elexacaftor, a next-generation corrector…