Posts by: Marta Figueiredo

cystic fibrosis, News

Blocking the interaction between two molecules involved in immune restraining mechanisms — called PD-1 and PD-L1 — may be an effective therapeutic strategy to boost the immune system and ... Read more

August 17, 2018

FDA Expands Kalydeco’s Approval to 1-year-old Toddlers with Cystic Fibrosis

News

The U.S. Food and Drug Administration (FDA) has approved Kalydeco (ivacaftor) as the first-ever therapy to treat the underlying cause of cystic fibrosis (CF) in 1-year-old toddlers, Vertex Pharmaceuticals announced. “Parents ... Read more

January 22, 2018January 22, 2018

Synspira Therapy Eliminates Antibiotic-resistant Lung Bacteria, Study Shows

cystic fibrosis, News

A therapy whose developers say could revolutionize the battle against antibiotic-resistant lung infections in cystic fibrosis patients eliminated resistant Staphylococcus aureus in a lab, a study reports. The finding dealt with Synspira’s polycationic ... Read more

December 18, 2017December 18, 2017

Cancer Gene, PTEN, Appears to Work with CFTR to Prevent Lung Infections, Study Reports

cystic fibrosis, News

One of the most frequently mutated genes in cancer, PTEN, in involved in the repeated lung infections that trouble cystic fibrosis patients — not because PTEN is abnormal in ... Read more

December 4, 2017December 5, 2017

Phase 1b Trial of ELX-02 to Possibly Treat Nonsense Mutations in CF and Other Diseases Begins

cystic fibrosis, News

Sevion Therapeutics and Eloxx Pharmaceuticals announced that a first healthy subject has been dosed in a Phase 1b clinical trial assessing the safety, tolerability and drug properties of ELX-02 as ... Read more

November 27, 2017November 29, 2018

CF Patients Increase Bacterial Load But Lose Bacterial Diversity As They Age, Study Finds

cystic fibrosis, News

Cystic fibrosis (CF) patients have more bacteria but lower bacterial diversity in their lungs than people without CF — yet bacterial diversity diminishs with age in CF patients, a ... Read more

November 21, 2017November 21, 2017

New Model Using Airway Cells May Help in Testing Potential CF Therapies, Study Says

cystic fibrosis, News

Scientists at the University of North Carolina (UNC) School of Medicine developed a model of cystic fibrosis (CF) that may help to test current and future CF therapies. This model, showing ... Read more

November 15, 2017November 15, 2017

Italians Find Molecule That Inhibits Anti-inflammatory and Anti-bacterial Defenses in CF

cystic fibrosis, News

Italian researchers have discovered a molecule that prevents cystic fibrosis patients’ anti-inflammatory and anti-bacterial defenses from working as well as they should. Scientists may be able to target the molecule, ... Read more

November 14, 2017November 14, 2017

Europe’s CHMP Gives Its Blessing to Vertex’s Orkambi as CF Therapy for Younger Children

cystic fibrosis, News

The European Union’s Committee for Medicinal Products for Human Use (CHMP) has issued a positive recommendation for Orkambi (ivacaftor/lumacaftor) as a therapy for cystic fibrosis (CF) in children. The ruling is specifically for ... Read more

Posts by: Marta Figueiredo

Marta Figueiredo

Immunotherapy May Be Promising Strategy to Treat Chronic Infections of P. aeruginosa in CF Patients

FDA Expands Kalydeco’s Approval to 1-year-old Toddlers with Cystic Fibrosis

Synspira Therapy Eliminates Antibiotic-resistant Lung Bacteria, Study Shows

Cancer Gene, PTEN, Appears to Work with CFTR to Prevent Lung Infections, Study Reports

Phase 1b Trial of ELX-02 to Possibly Treat Nonsense Mutations in CF and Other Diseases Begins

CF Patients Increase Bacterial Load But Lose Bacterial Diversity As They Age, Study Finds

New Model Using Airway Cells May Help in Testing Potential CF Therapies, Study Says

Italians Find Molecule That Inhibits Anti-inflammatory and Anti-bacterial Defenses in CF

Europe’s CHMP Gives Its Blessing to Vertex’s Orkambi as CF Therapy for Younger Children

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