Author Archives: Santiago Gisler

NIH Funds Fight Against CF-associated Antibiotic Resistant Bacteria

Researchers at Case Western Reserve University School of Medicine have received a $3.34 million grant from the National Institutes of Health (NIH) to develop a new strategy to sensitize Burkholderia multivorans — a common pathogen in patients with lung diseases like cystic fibrosis (CF) — to the action of…

Hyperbaric Oxygen Treatment May Make Antiobiotics More Effective Against P. aeruginosa Infections, Study Says

Exposing cystic fibrosis (CF) patients to high levels of oxygen through hyperbaric oxygen treatment may make Pseudomonas aeruginosa bacterial aggregates more sensitive to antibiotics like tobramycin and easier to eradicate from the lungs, a study in patient-derived bacterial cultures reports. The study, “Hyperbaric oxygen treatment increases killing of aggregating Pseudomonas aeruginosa isolates from…

Gene Expression Patterns in Blood May Lead to Patient-tailored CF Treatment, Study Finds

Researchers tested blood samples from cystic fibrosis (CF) patients and identified distinct gene expression patterns that could lead to patient-tailored treatments, a study reports. The study, “Identification of molecular signatures of cystic fibrosis disease status using plasma-based functional genomics,” was published in Physiological Genomics. To better understand…

CFF Aids Development of NO-based Therapy, BIOC51, for Resistant Bacteria, Vast Therapeutics Says

Vast Therapeutics announced that it received funding from the Cystic Fibrosis Foundation (CFF) to support further development of BIOC51, the company’s investigative treatment for antibiotic-resistant bacteria, including Pseudomonas aeruginosa, that is often the cause of lung infections in cystic fibrosis (CF) patients. P. aeruginosa infections set in when mucus accumulation…

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What It’s Like to Have a Family Member in the ICU

Main graphic for "Safe and Sound," Cystic Fibrosis News Today, by columnist Shelby Dell
Five years after her brother, Bradley, fought for his life in the ICU, columnist Shelby Dell reflects on how his hospitalization affected her.

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