Santiago Gisler,  —

Articles by Santiago Gisler

CF-associated Bacteria and Fungi Affect Each Other’s Growth, According to In Vitro Study

Physical and signaling interactions between two pathogen groups that often affect patients with cystic fibrosis (CF) — Pseudomonas aeruginosa bacteria and Scedosporium fungi — result in a growth effect (inhibition or enhancement) of these microorganisms, according to an in vitro study. CF therapies such as antibiotics or corticosteroids also affected the growth of the fungi, the…

Phase 2a Trial Will Test Molgradex in CF Patients with NTM Infections

Savara Pharmaceuticals has launched a Phase 2a clinical study to evaluate the effectiveness of Molgradex in cystic fibrosis (CF) patients with chronic nontuberculous mycobacterial (NTM) lung infections. Molgradex is an inhaled form of artificially produced human protein granulocyte-macrophage colony-stimulating factor (GM-CSF), which normally is produced and secreted by…