Due to persistent bacterial infections, long-chain fatty acids (LCFA) are linked to continued inflammation in cystic fibrosis (CF) patients — and may contribute to pulmonary exacerbations in children with CF, according to a recent study. The scientists said further studies are needed to examine how bacterial functions following antibiotic…
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Bronchitol (mannitol), an inhaled mucus-clearing treatment for cystic fibrosis (CF), is now commercially available in the U.S., according to Chiesi USA, which is marketing the therapy in the country. “We are excited to bring the first dry powder inhaled mucoactive agent to the U.S. for adults with CF,…
AzurRx BioPharma announced that its Phase 2b trial evaluating the safety and efficacy of MS1819 in treating exocrine pancreatic insufficiency (EPI) in cystic fibrosis (CF) patients is fully enrolled. Thirty adults with CF are taking part in the OPTION 2 study (NCT04375878) comparing MS1819 with the current standard…
Thanks to the Cystic Fibrosis Foundation (CFF), people with cystic fibrosis (CF) in the United States will receive free access to the online wellness and exercise platform Beam through the end of this year. “Wellness plays a critical role in an individual’s quality of life no matter what challenges…
A precise gene-editing tool that reverses single DNA mutations may lead to genetic therapies for people with cystic fibrosis (CF), a study suggests. The study, “Programmable C:G to G:C genome editing with CRISPR-Cas9-directed base excision repair…
One need look no further than the name of the Cystic Fibrosis Foundation‘s Impact Grant program to figure out what it does — helping those affected by cystic fibrosis (CF) serve their disease community in creative ways that matter. The CF Foundation is currently accepting applications for the 2021 award…
Molecular analysis of single cells lining the digestive tract found high CFTR activity — the gene associated with cystic fibrosis (CF) — in some cells in the duodenum, or first part, of the small intestine. A comparison of cells lining the stomach of…
Two bacterial species known to be frequent sources of lung infection in people with cystic fibrosis (CF) — Pseudomonas aeruginosa and Staphylococcus aureus — can feed each other with a nutrient called purine that both need to thrive, a study shows. Such interaction could determine the course of…
The use of oral nutritional supplements is associated with a higher intake of nutrients and better levels of certain vitamins in cystic fibrosis (CF) patients with poor respiratory and nutritional status. These results are found in the study “Oral nutritional supplements in…
Too often, cystic fibrosis (CF) patients or their caregivers do not follow proper hygiene procedures when cleaning, disinfecting and storing nebulizers, risking them being a source of lung infections. But proper training can help, a Turkish study reports. Healthcare providers should also be more aware of the potential for poor…
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