Nontuberculous mycobacteria (NTM), a type of infectious bacteria, is able to survive being dried for a full day, a study found, suggesting that drying is not a sufficient way to disinfect nebulizers used by people with cystic fibrosis (CF). The study, “Susceptibility of the Mycobacterium…
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A potential way of killing persistent bacterial infections like those common to people with cystic fibrosis (CF) — using nutrient channels that may exist within bacterial communities to carry antibiotics — is suggested by a research team at the University of Strathclyde in Glasgow. Their study, “…
AR-501, an inhaled treatment candidate for chronic lung infections in people with cystic fibrosis (CF), has been deemed safe and well-tolerated in healthy volunteers, results from the first part of a Phase 1/2a clinical trial show. The trial’s safety monitoring committee (SMC) and a data safety monitoring board…
Renovion has raised $8.1 million in a financing round, supporting further development and planned clinical testing of ARINA-1, a nebulized treatment for chronic lung diseases like cystic fibrosis (CF) and non-CF bronchiectasis, and for lung transplants. “Patient and laboratory studies have…
Eloxx Pharmaceuticals has resumed enrollment in its Phase 2 clinical trial evaluating ELX-02 in cystic fibrosis (CF) patients in Israel and Europe, after it was temporarily halted due to the COVID-19 pandemic. “We are pleased that enrollment in our Phase 2 clinical…
After being given more than $3 million from the Cystic Fibrosis Foundation (CFF) in 2017 to expand the development of viral vectors for gene delivery in the lungs, 4D Molecular Therapeutics (4DMT) now will receive up to $14 million from CFF to support the development of a…
Most people in the U.K. are unaware of the challenges faced by people living with cystic fibrosis (CF), according to results of a YouGov poll commissioned by the U.K. Cystic Fibrosis Trust. Data from the survey indicates that four of five people in the general public do not…
Exposure to second-hand smoke in infants and children with cystic fibrosis (CF) is linked to changes in levels of metabolites and activation of signaling pathways that enhance inflammation, a study has found. The findings suggest exposure to second-hand smoke is a potentially important environmental factor in CF. The study…
The third annual CF FamilyCon, a free and online event that connects people with cystic fibrosis (CF) and their extended families and friends with one another — and to others — takes place this weekend. This two-day event, supported by the Cystic Fibrosis Foundation, is set for…
A combination of two mutations, including one that had never been reported, were found in two Chinese siblings who developed a severe form of cystic fibrosis (CF), according to a case report. The report, “Identification of a Mutation in the Novel Compound Heterozygous CFTR in a…
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