How Cells Identify and Target Harmfully Folded Proteins, Like in CF, Detailed in Study
To become biologically active, most proteins must acquire a defined three-dimensional structure in processes that are mediated and monitored by molecular chaperones. Researchers based in Germany and the U.S., possibly for a first time,  have revealed how these chaperones identify particularly harmful errors in protein conformation, and induce their degradation. The…