News

ProQR Therapeutics is reporting that an early clinical study of  QR-010 in cystic fibrosis patients homozygous for the ΔF508 mutation in the CFTR gene met its primary endpoint. After four weeks of treatment, these patients showed a positive change in total chloride response, meaning that the CFTR protein was again working. In patients heterozygous for…

Verona Pharma recently announced that it has received its second Venture and Innovation Award from the U.K. Cystic Fibrosis Trust. The award will help fund a Phase 2 clinical trial to investigate RPL554 as a possible treatment of cystic fibrosis (CF). The trial, which expects to start recruiting CF patients during the first…

Early lab and animal studies suggest that Spyryx Biosciences’ drug candidate SPX-101 will be a safe and effective way of  improving mucus clearance in patients with cystic fibrosis (CF), regardless of the underlying mutation(s) causing their disease. The data were presented at the 30th Annual North American Cystic Fibrosis…

The Boomer Esiason Foundation (BEF) announced the Sacks for CF Scholarship for 2016-17, which are funding grants for college students who have cystic fibrosis (CF). Awards for undergraduates and graduates of $3,000 to $10,000 are given annually to 30 college students who strive for adherence to daily CF therapy,…

Alcresta Therapeutics announced that its product RELiZORB effectively increased fat absorption in cystic fibrosis (CF) patients receiving enteral tube feeding and who have trouble breaking down and absorbing these molecules, resulting in reduced frequency and severity of gastrointestinal symptoms among those patients. The findings were presented at the 30th…

A transition from youth to adult cystic fibrosis (CF) care needs to be guided by formal programs to maximize patient satisfaction and health outcomes. For successful transitions, skills essential to managing independent adult care also need to be developed, and assessing such skills before attempting a transfer would be wise. The “…

In a recent talk titled “Implementation of Colorectal Guidelines,” Alexander Khoruts, MD, from the University of Minnesota, discussed recommendations for an effective screening for colorectal cancer in patients with cystic fibrosis (CF). The talk was presented at the 30th Annual North American Cystic Fibrosis Conference Oct. 27-29 in Orlando, Florida. Patients…

Substantial health benefits can be gained by cystic fibrosis (CF) patients who exercise more, but to accurately assess the impact of such interventions, physicians need to test for exercise capacity and habitual physical activity. In the session, “Let’s Get Moving: Best Practices in Exercise & Physical Activity…

The importance of investigating the role of the airway microbiome in lung damage associated with cystic fibrosis (CF) was the focus of two talks at the recent 30th Annual North American Cystic Fibrosis Conference (NACFC) in Orlando, Florida. Both talks were based on the topic, “Microbiome Studies Can be Helpful in Understanding CF Infections.” CF and CF manifestations, particularly…

Developing a vaccine against infections in patients with cystic fibrosis (CF) is challenging, and to succeed researchers need a deeper understanding of the natural history of CF lung infections. Joanna Goldberg, PhD, with Emory University School of Medicine, detailed the difficulties specific to such vaccine discovery in her talk, “Vaccines for CF Infections: Episode…