News

Galapagos and AbbVie Present New Cystic Fibrosis Treatment Projects at ECFS Conference

Galapagos NV, a clinical-stage biotechnology company, recently delivered a joint presentation with AbbVie during the 38th annual conference of the European Cystic Fibrosis Society held in Brussels, Belgium. The presentation revealed co-developed technologies to address CF, part of Galapagos’ pipeline that includes three Phase 2 programs, two Phase 1 trials, five pre-clinical studies, and…

Endogenous Lung Stem Cells and Cystic Fibrosis, an Introduction

My past few articles have touched upon the application of stem cells for the treatment of cystic fibrosis (CF), and while some of these treatments demonstrate great promise for the future of CF, it is important to establish more necessary discourse. With my past articles discussing Embryonic Stem Cells (ESCs),…

Another Study Reveals Positive Results in Fighting P. Aeruginosa

AmpliPhi BioSciences Corporation, a global leader in the development of bacteriophage-based antibacterial therapies to treat drug resistant infections, announced study results for a trial looking at a novel treatment strategy for cystic fibrosis (CF) patients. The results, which suggested that bacteriophages remain active against Pseudomonas aeruginosa (P. aeruginosa)…

UK’s Cystic Fibrosis Trust Appoints First-Ever “Director Of Impact”

The Cystic Fibrosis Trust recently announced its first-ever appointment of a “Director of Impact” to spearhead the organization’s commitment to improve care, support and research for those with CF in the United Kingdom. Dr. Keith Brownlee boasts a proven record of experience and expertise as a cystic fibrosis specialist pediatrician, having worked for more than 20…

Celtaxsys Raises $45M For Novel Anti-inflammatory CF Drug Phase 2 Research

The lead drug candidate under development by Celtaxsys — an Atlanta, Georgia based clinical-stage development company focused on novel therapeutics for treating inflammatory disease through regulation of immune cell migration and activation — is CTX-4430, described as a potent, oral, once-daily, small-molecule LTA4 Hydrolase (LTA4H) inhibitor that shows promise as…

Vertex and Parion Sciences to Co-Develop Epithelial Sodium Channel (ENaC) Inhibitors in Cystic Fibrosis

Vertex Pharmaceuticals Incorporated  and Parion Sciences recently announced a joint collaboration for the development of investigational epithelial sodium channel (ENaC) inhibitors to treat cystic fibrosis (CF) and other pulmonary conditions. Based on the agreement rights, Vertex will develop and commercialize Parion’s ENaC inhibitors, named P-1037 and P-1055, for…