A study reported that treating a mouse model of cystic fibrosis (CF) with the antibiotic streptomycin eased the animals’ airway hyper-responsiveness. The improvement in airway function was accompanied by an altered immune profile and changes in a certain bacteria in the gut. The study, titled “Streptomycin treatment…
News
Ian Ross Pettigrew, the Hamilton, Ontario-based photographer and the creator of the Salty Girls photo project and book of the same name, is carrying on with the next stage of his project: capturing images of people living with cystic fibrosis (CF). Salty Kids will containing a gallery of images of children with…
Nivalis Therapeutics announced that the U.S. Food and Drug Administration (FDA) has granted its lead investigational drug, N91115, orphan drug status for the treatment of cystic fibrosis (CF). Drug candidate N91115 is a stabilizer of the CF transmembrane conductance regulator (CFTR) protein. Orphan drugs are generally those with a limited…
A recent study in the American Journal of Critical Care Medicine suggested a new therapeutic target for cystic fibrosis (CF), and reinforced the idea that inflammation is an acquired response unrelated to the CFTR genetic mutation. The study is titled “X-Box–Binding Protein 1 and Innate…
Vertex Pharmaceuticals, a biotech company that discovers, develops, and commercializes medicines for a series of diseases, currently with a clinical development program focused on cystic fibrosis (CF), recently announced its key business priorities for 2016. Vertex currently has two medicines approved for cystic fibrosis treatment: KALYDECO (ivafactor) and ORKAMBI (lumacaftor/ivacaftor).
University of New Mexico researcher Graham Timmins has developed a diagnostic breath test, known as the urease test, that has the potential to rapidly confirm diseases like tuberculosis (TB) by detecting bacterial enzymes (ureases) in the lungs. The test was developed for TB, but Dr. Timmins plans to investigate its efficacy in other lung…
A recent study published in the journal Pediatrics showed that depression in parents of children with cystic fibrosis (CF) negatively impacts treatment adherence in children taking enzyme supplements. The findings point to the possibility of increasing adherence rates by identifying and treating parental depression. Studies showed that good…
Keiser University has raised $50,000 to support the Cystic Fibrosis Foundation through the efforts of its staff and students across 17 campuses in Florida. This is the ninth year Keiser has taken part in a fundraising event for the foundation. The 2015 campaign adopted a “Terminator”-inspired movie theme for activities that raised money to further research and care into cystic fibrosis (CF),…
A new research study may help establish racial equity in cystic fibrosis (CF) newborn screening programs where identification of gene variants in non-white individuals remains suboptimal when compared to the white population. The research paper, “The Spectrum of CFTR Variants in Nonwhite Cystic Fibrosis Patients,” was published in…
A study found that cystic fibrosis (CF) patients, especially younger patients, may be at increased risk of acute cellular rejection of transplanted tissues compared to other transplant patients. The study, “Higher Risk of Acute Cellular Rejection in Lung Transplant Recipients with Cystic Fibrosis,” was recently published in the journal …
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