Author Archives: Margarida Azevedo, MSc

Vertex Enrolling Patients with CF in Three, Phase 3 Studies of VX-661 and Kalydeco Combo Therapy

Vertex Pharmaceuticals recently gave an update on its Phase 3 development program, which consists of four studies, on the investigational compound VX-661 in combination with Kalydeco (ivacaftor) as a treatment of patients with cystic fibrosis (CF). The company plans to terminate one study, which is investigating VX-661 plus ivacaftor in people with one copy of…

Data, Published by Company, Shows AffloVest Device Helps CF Patients with Airway Clearance

International Biophysics Corporation recently announced the publication of new data regarding the effectiveness of its AffloVest airway clearance technology in patients with cystic fibrosis. The paper, “Lung function improvement with AffloVest® HFCWO use: a clinician’s perspective on PFT score data from 12 patients with cystic fibrosis,” was published on the…

Newborn Screening for CF Linked to Better Pubertal Growth and Adult Height

People whose cystic fibrosis was detected through screening programs for newborns were found to have better growth throughout puberty and superior adult height, compared to those whose CF was diagnosed after they began exhibiting symptoms, researchers at the University of Wisconsin–Madison reported. The study, based on analyzed data from the Wisconsin Randomized Clinical Trial, “Pubertal Height…

New Antimicrobial Peptide May Be Able to Treat Even Drug-Resistant CF Lung Infections

Researchers at the University of Pittsburgh Center for Vaccine Research (CVR) have developed an engineered antimicrobial peptide effective against co-infection by bacterial microfilm and a virus, and as such is a possible new therapeutic agent against chronic and antibiotic-resistant infections. Importantly, the potential drug was tested against Pseudomonas aeruginosa, one of the primary and more dangerous…

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How to Ask for and Offer Help

A banner for Kate Delany's "Breathe and Believe" column that depicts a pair of lungs with flowers blossoming from them.
In times of need, we may not know how to ask for help or offer it to others. Columnist Kate Delany shares helpful tips on how to do it.

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