Author Archives: Ana Pamplona, PhD

Clinic-based CF Study Links Repeat Hospitalizations to Repeat MRSA Infections

A new study of children with cystic fibrosis found that co-infection with methicillin-resistant bacteria may be associated with increased pulmonary morbidity, especially in children with repeat hospitalizations. The retrospective study, conducted at a U.S. pediatric medical center with high rates of methicillin-resistant respiratory infections, is titled “Clinical characteristics and…

Targeted Antibiotics Focus of New Cystic Fibrosis Study

A new study entitled “Lung Microbiota Changes Associated with Chronic Pseudomonas aeruginosa Lung Infection and the Impact of Intravenous Colistimethate Sodium,” published in the PLOS One journal, highlights the potentially positive impact of intravenous antibiotic colistimethate sodium in the proportion of Pseudomonadales relative to other Gram-negative…

Managing the Steps in Cystic Fibrosis Pulmonary Flare-ups

A new study entitled “Respiratory microbiota resistance and resilience to pulmonary exacerbation and subsequent antimicrobial intervention,” published in The International Society for Microbial Ecology Journal, investigated how bacterial communities in the lung change over time in relation to the disease state and progression of…

CF Protein Tied to Intestinal Inflammation in Study

A new study revealed that the cystic fibrosis transmembrane conductance regulator (CFTR) plays an important role in regulating the intestinal inflammatory responses. The study, entitled “CFTR Knockdown induces pro inflammatory changes in intestinal epithelial cells,” was published in the Journal of Inflammation…

CF Pathogen Defies Treatment Attempt with Novel Drug Combination

A new study revealed that treating P. aeruginosa biofilms with the antibiotic tobramycin together with mannitol — two well-known therapies in treating lung infections in CF — did not reduce overall bacterial load. The study entitled “Mannitol Does Not Enhance Tobramycin Killing of Pseudomonas aeruginosa in a Cystic Fibrosis Model System…


Featured Column

The Benefits of Being Sick

A banner for Lara's column, depicting a car on a road trip winding through a forest.
As columnist Lara Govendo reflects on her journey through CF and transplant, she realizes there are a surprising number of benefits.

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