Galapagos NV, a developmental stage biotechnology company working on small-molecule and antibody programs in cystic fibrosis, inflammation, antibiotics and metabolic diseases, announced it has launched the first Phase I study of GLPG1837, a potentiator formulated as a CFTR-targeted therapy for cystic fibrosis (CF) cases caused by class III/IV mutations. In order…
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Lung transplantation patients who are treated with immune-suppressing drugs after surgery to prevent rejection of the lung are susceptible to contracting life-threatening viruses such as cytomegalovirus (CMV). In order to protect against this, lung transplant patients are normally treated with an anti-viral drug called ganciclovir, which decreases mortality caused…
The Cystic Fibrosis Trust recently announced that it would serve as the official charity partner of the British Comedy Awards for their 25th Anniversary special on December 17, 2014. Before the ceremony officially began, a very special video from the Trust made its debut in front of a star-studded…
The rise in bacterial strains that are highly resistant to antibiotics is a growing health concern, as the research community scrambles to discover new alternatives to treating bacterial infections. This concern is particularly heightened in the cystic fibrosis community, where effective antibiotics are crucial in curtailing what could become…
The All-Party Parliamentary Group (APPG) on Cystic Fibrosis was officially launched this Tuesday in the United Kingdom’s House of Commons, with support from politicians and policy makers across the entire political spectrum in the UK in endorsing the Cystic Fibrosis Trust as an effective advocate for fighting the disease…
A new study entitled “Pulsed direct and constant direct currents in the pilocarpine iontophoresis sweat chloride test,” recently published in the journal BMC Pulmonary Medicine, compared the production and volume of sweat, side effects caused by pulsed direct current, and constant direct current, and sought to determin the…
Galapagos is a company specializing in novel mechanisms of small-molecule and antibody programs for cystic fibrosis. In a recent press release, the company revealed that before the end of 2015, they are going to conduct a Phase 1 clinical trial of a new corrector called GLPG2222 in conjunction…
Specialty biopharmaceutical company Shire has just announced a new partnership with the Cystic Fibrosis Foundation to develop technology that can maintain and/or restore lung function, as well as protect against respiratory infections — two primary health concerns in people living with cystic fibrosis (CF). The announcement was made…
A new study from a team of researchers of the University of Pittsburgh Center for Vaccine Research (CVR), entitled “Engineered Cationic Antimicrobial Peptides (eCAPs) to Overcome Multidrug Resistance by ESKAPE Pathogens” demonstrated the effectiveness of new antibiotic agents as inhibitors of the growth of drug-resistant bacteria. The findings…
The Mauli Ola Foundation’s (MOF) 2014 national Ohana Tour will finish on the North Shore of Oahu, and the event will include pediatric visits and Surf Experience Days to help those suffering with cystic fibrosis. Jamie O’Brien, the pipeline master, will be hosting the final 2014 Surf Experience which…
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