Vertex Pharmaceuticals‘ two-part proof-of-concept study evaluating ivacaftor (under the name KALYDECO) in 24 cystic fibrosis patients shows data consistent with previous preclinical observations. An eight-week open-label period resulted in improved lung function in patients, initiating plans for a future Phase 3 trial. Each of the 24…
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A group of thirteen scientists at the University of North Carolina School of Medicine may know why certain cystic fibrosis treatments improve lung function. Their answer: mucins, the proteins within mucus. “Our finding suggests that diluting the concentration of mucins in cystic fibrosis mucus is a key to better…
In some ways, it’s both the best of times and the worst of times for persons afflicted with certain serious disease conditions, such as cystic fibrosis. On the one hand, there have been encouraging and potentially life-changing breakthroughs in terms of therapy options. On the other, these new drugs can…
People with cystic fibrosis can be prone to developing diabetes. However, only recently have researchers learned that the onset of diabetes occurs due to a mutation in a molecular mechanism that increases the risk of developing the disease. As a result, researchers from Lund University in Sweden and Karolinska…
Price Of CF Drug Kalydeco Could Drop In Canada And Australia Under New Public Health Care Deals
Canada’s CTV News reported late last week that the province of Alberta’s health minister has successfully negotiated a tentative deal that will allow Canadian provinces to cover the cost to their provincial pharmacare plans of the multiple sclerosis (MS) drug Kalydeco, used for treatment of cystic fibrosis (CF)…
A recent study led by GBI Research entitled “Cystic Fibrosis Therapeutics in Major Developed Markets 2019 – CFTR Modulators Initiate Drive Towards Personalized Treatment and Market Growth,” notes that the Cystic Fibrosis market will grow from $695.6 million in 2012 to near a $ 4.5 billion in 2019 in…
Austin-based International Biophysics Corporation’s marquee product, AffloVest, is a cutting-edge technology airway clearance vest that represents a major advance in treatment of respiratory diseases such as Cystic Fibrosis (CF), Chronic Obstructive Pulmonary Disease (COPD), chronic bronchitis, and similar related ailments. This High Frequency Chest Wall Oscillation (HFCWO) vest that gives…
According to an exclusive report from Fox Sports 1, a scout for the Miami Dolphins is considering a lawsuit for allegedly being fired as a result of telecommuting to work in order to care for his wife who has Cystic Fibrosis, after recently losing healthcare coverage for her…
Bacterial infections pose a major health risk in cystic fibrosis patents, which can lead to hospitalization and life-threatening health issues. As a result, the research community continues to focus on new therapies that effectively treat CF patients for common bacterial infections in the lungs while also facilitating patient compliance.
The Walgreens Alliance Pharmacy has announced that it is now offering a new program that provides medication instruction, support, and continuing guidance to patients with cystic fibrosis (CF). The personalized Connected Care Cystic Fibrosis Management Program aims to help people live longer and healthier lives, and will be accessible…
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