News

The triple combination therapy Kaftrio restores the function of CFTR — the defective protein in cystic fibrosis (CF) — and associated chloride and bicarbonate flow in gastrointestinal “mini-organs” derived from a patient carrying the most common CF-causing mutation, a study shows. These findings highlight the benefits of Vertex…

The Boomer Esiason Foundation is awarding $150,000 in scholarships to students within the cystic fibrosis (CF) community who want to pursue higher education in the U.S. To win one of the 15 grants worth $10,000 each, applications must be submitted on this online form by the April 29…

Infection with the environmental bacteria Achromobacter in children with cystic fibrosis (CF) is linked with poorer lung function and more pulmonary exacerbations, a study suggests. These findings highlight the need to identify Achromobacter infection promptly so that children can receive appropriate treatment.  “Our results may indicate that…

People with cystic fibrosis (CF) can have a complicated relationship with food and eating that changes over their lifetime, a series of patient interviews regarding diet reveals. For many patients, bad childhood experiences — needing feeding tubes and having to pack on more weight — impacted their perceptions of…

Cystic fibrosis (CF) patients show a shift in gut microbiota composition toward more abundant, rarer populations that is significantly associated with antibiotic use, CF disease, and CF-associated changes in gut function and transit, a study shows. These findings add to previous studies showing that CF patients have reduced gut…

Monocyte immune cells from bone marrow partially transplanted into a mouse model of cystic fibrosis (CF) improved survival and reduced inflammation, a study found. Meanwhile, transplanting monocytes from CF mice into healthy mice triggered CF-like symptoms and limited survival, suggesting that these defective immune cells may cause symptoms, the…

The Cystic Fibrosis Foundation has awarded funding to Feldan Therapeutics to develop the Feldan Shuttle, a technology designed to deliver medicines directly inside the epithelial cells that line the airways in people with cystic fibrosis (CF). Awarded as part of the foundation’s $500 million Path to…

Mallory Smith was a poster child for cystic fibrosis (CF). She was a three-sport varsity athlete in high school, was accepted into Stanford University, and was consistent with her therapies, medications, and nutrition. Her smile and positive energy were felt by friends and family. On the inside, however, no…

Poorer growth in childhood is associated with shorter height as adults in people with cystic fibrosis (CF) and does not appear to be linked with nutritional status, a recent study reported. Results of the study, “Most Short Children with Cystic Fibrosis Do Not Catch…

First Wave BioPharma has filed two new patents related to adrulipase, a yeast-derived enzyme that the company is developing to treat exocrine pancreatic insufficiency in people with cystic fibrosis (CF). One application is related to dosage forms, methods of treatment, and manufacturing methods for the investigational medication. This includes a…