What are the side effects of taking CFTR modulators?

CFTR modulators may cause side effects that include cold-like symptoms (runny nose, congestion, etc.) and gastrointestinal effects — nausea, diarrhea, and abdominal pain — as well as headache, dizziness, rash, infections, cataracts, and liver damage. The specific side effect profile varies depending on the particular cystic fibrosis medication; patients are advised to consult with their healthcare providers about any effects they experience after starting on CFTR modulator therapy.