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News

CF families want care teams to help them manage school needs

People with cystic fibrosis (CF) and their caregivers want their CF care teams to help with school needs, including absences, accommodations, and infection control, according to a U.S. survey. The survey revealed common issues…

News

40% of patients on CFTR modulators see inhaled medicines as less important

About 40% of people with cystic fibrosis (CF) taking CFTR modulators, a class of medication used to treat the genetic disorder, consider inhaled medicines less important after starting these meds, according to a U.K.

News

Antifungals plus steroids show no added benefit for ABPA in CF study

Adding antifungal therapy to oral corticosteroids was not associated with additional benefits for people with cystic fibrosis (CF) being treated for allergic bronchopulmonary aspergillosis (ABPA), a large U.S. real-world study found. ABPA is a…

News

CF treatment helps sinus symptoms, weight after lung transplant

Treatment with Trikafta (elexacaftor/tezacaftor/ivacaftor) eased sinus symptoms and helped stabilize weight without evidence of worsening lung function in people with cystic fibrosis (CF) who had received a lung transplant, a study found. The…

News

Shared metabolic pathway may drive CF lung infections, study finds

A metabolic pathway shared by lung cells and bacteria may help explain two major features of lung disease in people with cystic fibrosis (CF): the gradual thickening of the airways and persistent lung infections.

News

Indoor air pollution tied to changes in CF inflammatory markers

Adults with cystic fibrosis (CF) who spent more time in homes with elevated indoor fine-particle levels tended to show changes in circulating inflammatory signaling proteins, a pilot study found. Researchers measured more than 40…

News

Chemical changes affecting genes help explain differences in CF, per study

French scientists have found that distinct patterns of DNA methylation — a type of chemical change that influences how genes are used without altering the underlying DNA sequence — are associated with cystic fibrosis…

News

CF treatment may reverse pancreatic damage in young children

In young children with cystic fibrosis (CF), treatment with Alyftrek (vanzacaftor/tezacaftor/deutivacaftor) may reverse a form of pancreatic damage previously thought irreversible. That’s according to Vertex Pharmaceuticals, Alyftrek’s developer, which presented new data…

News

CF treatment helps patients be more productive at work, in daily life

One year of Trikafta treatment boosted work productivity and daily activities for people with cystic fibrosis (CF), a real-world study from Canada showed. The gains stemmed from improvements in lung function, physical functioning,…

News

CF therapy linked to shifts in gut and lung microbiome activity

Kaftrio, a CFTR modulator marketed as Trikafta (elexacaftor/tezacaftor/ivacaftor) in the U.S., was associated with improved lung function and nutritional status in a study. Researchers found only small changes in which microorganisms were present, but…

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