News

Close monitoring urged for weight gain with Kaftrio in CF patients

While treatment with Kaftrio (elexacaftor/tezacaftor/ivacaftor) helps people with cystic fibrosis (CF) gain weight, a tendency toward unhealthy diets may pose new risks for patients — warranting “close monitoring and interventions to prevent excessive weight gain” — a study from Norway reports. People with CF in the European nation who…

A CF patient advocate’s mission is to improve clinical trials

As a child, Ella Balasa was no stranger to hospital stays. Diagnosed with cystic fibrosis (CF) at 18 months, she faced persistent lung infections that often required weeks-long courses of antibiotics, multiple times a year. “I was always in the hospital needing treatment,” Balasa, now 33 and living in…

Antibiotic azithromycin boosts lung function in young people with CF

Treatment with the antibiotic azithromycin improves breathing while slowing lung function decline over time in children and teens with cystic fibrosis (CF), according to a meta-analysis of published studies. “These findings not only provide a new perspective for clinical treatment but also reveal potential mechanisms of azithromycin in the…

CF Foundation invests $3M in experimental therapy RCT2100

The Cystic Fibrosis Foundation has made an additional $3 million investment in Recode Therapeutics to support clinical development of RCT2100, an investigational therapy for cystic fibrosis (CF) that is currently being tested in patients who cannot take CFTR modulators. The CF Foundation had previously invested $15 million…

Blood test in pregnancy accurately diagnoses CF: Study

The Unity Fetal Risk Screen, a test that uses a pregnant person’s blood to evaluate the fetus’s risk of cystic fibrosis (CF), accurately detected all cases of CF in a study involving more than 100,000 pregnant people. The study found that most CF cases identified by the test are…

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