Author Archives: Ana Pamplona, PhD

Study Finds That Pseudomonas Aeruginosa’s Ability to Adapt in CF Exacerbates Pulmonary Inflammation

A new study revealed that adaptive changes in Pseudomonas aeruginosa may exacerbate pulmonary inflammation and contribute to the pathogenesis and progression of chronic lung disease in the context of cystic fibrosis. The study entitled “Cystic fibrosis–adapted Pseudomonas aeruginosa quorum sensing lasR mutants cause hyperinflammatory responses” was published in July in the Science Advances journal.

miRNAs Offer Potential New Targets for Cystic Fibrosis Gene Therapy

A new study revealed that microRNA16 — a small non-coding RNA genes that regulates gene expression — can restore the F508del-CFTR protein function in airway cell lines and primary cultures of differentiated human bronchial epithelia from F508del homozygotes that express mutant CFTR protein endogenously. The finding is significant, as…

Experimental Antibiotics Shown to Kill Bacterial Infection Frequently Found in Cystic Fibrosis

During the American Thoracic Society 2015 International Conference being held in Denver, Colorado, 15-20 of May, researchers from Oregon State University, Corvallis (OSU), and Aradigm Corporation will present a study entitled “Treatment of Mycobacterium Avium Subsp Hominissuis (MAH) Lung Infections with Liposome-Encapsulated Ciprofloxacin Resulted in Significant Decrease in Bacterial Load in the…

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How I Discovered That PTSD Was Causing My Post-transplant Struggles

PTSD, mental health, communities, stress, grateful, work, trauma, rare disease day, transplant, CF community, National Blood Donor Month, birthdays, holidays
Columnist Lara Govendo addresses an issue that several readers may relate to: post-transplant PTSD, which can wreak havoc.

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