Lindsey Shapiro, PhD, science writer —

Lindsey earned her PhD in neuroscience from Emory University in Atlanta, where she studied novel therapeutic strategies for treatment-resistant forms of epilepsy. She was awarded a fellowship from the American Epilepsy Society in 2019 for this research. Lindsey also previously worked as a postdoctoral researcher, studying the role of inflammation in epilepsy and Alzheimer’s disease.

Articles by Lindsey Shapiro

Trikafta Boosts Glucose Tolerance in CF Adults in Small Study

At least three months of using the triple combination therapy Trikafta (elexacaftor/tezacaftor/ivacaftor) significantly increased glucose tolerance — reflecting better control of blood sugar levels — in adults with cystic fibrosis (CF), a small study found. Production of insulin, the hormone that helps clear glucose from the bloodstream, wasn’t…

Gut-lung Axis Likely in CF, High-fat Diet May Drive Inflammation

Children with cystic fibrosis (CF) show significant differences from healthy children in the quality of their food choices and, subsequently, the microbes in their gut and respiratory tract, with evidence of greater intestinal inflammation in these young patients, a recent study in Australia found. Certain microbes in the gut associated…

First Patient Dosed in Trial of Phage Therapy for Lung Infections

The first patient has been dosed in a Phase 1b/2 clinical trial testing WRAIR-PAM-CF1, an investigational bacteriophage therapy, in adult cystic fibrosis (CF) patients with chronic Pseudomonas aeruginosa lung infections. The PHAGE trial (NCT05453578) is recruiting an estimated 72 such patients who tested positive for a P. aeruginosa infection…

Renexxion Seeks FDA OK to Test Naronapride for GI Problems in CF

Renexxion is seeking clearance from the U.S. Food and Drug Administration (FDA) for clinical testing of the treatment candidate naronapride in people with cystic fibrosis (CF) and gastrointestinal (GI) problems. The Ireland-based biopharmaceutical company, which specializes in treatments for gastrointestinal disorders, announced the opening of an investigational new…

A Conversation With Rare Disease Advocates

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