Magdalena Kegel,  —

Cayston (aztreonam) was deemed the best treatment across a range of parameters in a study comparing inhaled antibiotic treatments against Pseudomonas  (P.) aeruginosa lung infections in patients with cystic fibrosis (CF). But the study also demonstrated that Quinsair (levofloxacin inhalation solution) came in as a good second, improving lung function better than…

Early lab and animal studies suggest that Spyryx Biosciences’ drug candidate SPX-101 will be a safe and effective way of  improving mucus clearance in patients with cystic fibrosis (CF), regardless of the underlying mutation(s) causing their disease. The data were presented at the 30th Annual North American Cystic Fibrosis…

A transition from youth to adult cystic fibrosis (CF) care needs to be guided by formal programs to maximize patient satisfaction and health outcomes. For successful transitions, skills essential to managing independent adult care also need to be developed, and assessing such skills before attempting a transfer would be wise. The “…

Substantial health benefits can be gained by cystic fibrosis (CF) patients who exercise more, but to accurately assess the impact of such interventions, physicians need to test for exercise capacity and habitual physical activity. In the session, “Let’s Get Moving: Best Practices in Exercise & Physical Activity…

Developing a vaccine against infections in patients with cystic fibrosis (CF) is challenging, and to succeed researchers need a deeper understanding of the natural history of CF lung infections. Joanna Goldberg, PhD, with Emory University School of Medicine, detailed the difficulties specific to such vaccine discovery in her talk, “Vaccines for CF Infections: Episode…

There is not enough data to assess the effectiveness of birth control options in women with cystic fibrosis (CF), in whom an unplanned pregnancy may carry substantial risks for both the mom and the fetus. A session titled “Interesting Challenges in Women’s Health in Cystic Fibrosis,” discussed these topics in…

Fewer than half of the cystic fibrosis (CF) patients eligible for treatment with Orkambi (lumacaftor/ivacaftor) used the medication at the end of its first year on the market, an especially low number when compared to the spread of Kalydeco (ivacaftor) use. The study, “Uptake of Lumacaftor-Ivacaftor Use…

Patients with very advanced cystic fibrosis (CF) lung disease who get a lung transplant have the same chances of survival as CF patients with more stable disease, according to a recent study. The findings suggest that lung transplants are not only appropriate for the sickest patients, but the approach is…

Differences in survival between adults with cystic fibrosis (CF) in Canada and the U.S. likely are explained by a delayed introduction of nutritional support for patients, according to a recent study. However, the findings, presented at the 30th Annual North American Cystic Fibrosis Conference (NACFC), held in Orlando, Florida…

A recent study revealed that many patients with cystic fibrosis (CF), as well as parents, are not aware of what the palliative care encompasses, and how it could be helpful to people with CF and their families. CF care providers, for this reason, need to be trained in discussing the topic of…