Marisa Wexler, MS,  senior science writer—

A study will explore why some people with cystic fibrosis (CF) respond better to Trikafta than others. The five-year study, led by Arkansas Children’s Research Institute, is being funded through a $2.9 million grant from the National Institutes of Health (NIH). The project is being led by Jennifer…

A high dose of vitamin D combined with inulin, a prebiotic, led to improvements in the diversity of bacteria living in the airway and lungs of people with cystic fibrosis (CF) in a small clinical trial. The findings in the study, “Impact of high-dose cholecalciferol (vitamin…

Positivo Biotechnology, a company working to develop new gene therapy technologies for cystic fibrosis (CF), has been selected as the winner of this year’s Golden Ticket Award. The award, launched last year by the Cystic Fibrosis Foundation and the University of California, Berkeley’s Bakar Labs, aims to…

Even though most people with cystic fibrosis (CF) place considerable importance on being prepared in making decisions about a lung transplant, many lack knowledge of the procedure and speak of feeling unprepared, especially those of lower socioeconomic status, a survey of adults at a University of Washington CF clinic…

Genexys Biomed has been awarded a $320,000 grant to advance the development of a novel gene therapy for cystic fibrosis (CF). The small business innovation research grant was given by the National Heart, Lung, and Blood Institute, a branch of the National Institutes of Health. The “grant is a…

The first cystic fibrosis (CF) patient has been dosed in Part A of a Phase 2 clinical trial in Europe that’s testing Enterprise Therapeutics‘ novel CF treatment candidate ETD001. The Phase 2a trial (NCT06478706) is still recruiting adults with CF at a few sites in the U.K. and…

Authorities in the U.S. and Europe are reviewing applications from Vertex Pharmaceuticals seeking approval of the company’s novel CFTR modulator triple combination, vanzacaftor, tezacaftor and deutivacaftor.  Vertex is asking that the vanza combo be approved for people with cystic fibrosis (CF) ages 6 and older who carry…

During pulmonary exacerbation in cystic fibrosis (CF), bacterial communities in the lungs tend to change in one of two general patterns, and better understanding these patterns may help predict how patients will respond to antibiotic treatments. That’s according to the study, “Microbial community organization designates distinct…

Two Massachusetts-based companies, Nanite and Saliogen Therapeutics, are teaming up on a new research project that aims to create a genetic medicine with the potential to treat cystic fibrosis (CF). “Nanite’s relationship with SalioGen is consequential in discovering safe polymeric nanoparticles for a transformative treatment for CF,”…

This year’s “Fishing for a Cure,” an annual fundraiser hosted by Constellation Energy Corporation, has raised $70,000 for the Cystic Fibrosis Foundation, a nonprofit that helps to support people living with cystic fibrosis (CF) and to fund research for new treatments. “We are in shock by the incredible…