cystic fibrosis

Growing cells in artificial tracheas or lungs is a better approach to model native organs than cells cultured in spheroids or in a plastic filter, according to a study, suggesting that these platforms may be more suitable to study cell-based therapies for lung diseases such as cystic fibrosis (CF).

Pulmonary artery enlargement is linked to pulmonary hypertension (PH) and lower survival among patients with severe cystic fibrosis (CF), according to a recent review of patient records. The study reporting the findings, titled “Pulmonary artery enlargement is associated with pulmonary…

The non-profit organization Claire’s Place Foundation has launched a donation-based COVID-19 Emergency Fund to support the cystic fibrosis (CF) community by raising funds to provide patients and their families with groceries, supplies, and medications during the outbreak. The fund will be available for people with CF and…

Prolonged use of the antibiotic azithromycin resulted in a 37% slower rate of lung function decline in cystic fibrosis (CF) patients with persistent Pseudomonas aeruginosa infection over a three-year period, a study found. The study, “Pulmonary Outcomes Associated with Long-Term Azithromycin Therapy in Cystic…

The Cystic Fibrosis Foundation has awarded up to $5 million to Armata Pharmaceuticals to advance its potential treatment AP-PA02 — a phage therapy against multidrug-resistant Pseudomonas aeruginosa infections in cystic fibrosis (CF) patients — into a Phase 1b/2 clinical trial. Phage therapy harnesses the properties of …

A video game aimed at encouraging young cystic fibrosis (CF) patients to do their breathing exercises is being tested at Great Ormond Street Hospital in London and other sites across the U.K. Konglomerate Games, a company comprised of fourth-year students from Abertay University in Scotland, developed…

Kristine Durkin, a West Virginia University graduate student, is carrying out a study to assess whether teenagers with cystic fibrosis (CF) are meeting their nutritional requirements, and identify ways to help them improve their diets. CF teenagers often struggle to maintain healthy weight. They usually receive two to three…

Canadian patient advocates and leaders in the field of cystic fibrosis (CF) are meeting with Canadian government officials to lobby for changes to proposed regulatory reforms that are preventing CF patients from accessing Vertex’s new breakthrough therapy, Trikafta. Trikafta, Vertex’s most recent FDA-approved medication for the…

A new variation of the gene-editing technology CRISPR-Cas9 can correct mutations in the CFTR gene — the genetic cause of cystic fibrosis (CF) — in stem cells from CF patients, a study shows. The new approach has the ability to correct mutations without the need to excise the affected region,…

When Laura Bonnell, founder and president of the Bonnell Foundation, was 12 years old, she decided to become a reporter. That dream led to a long career at WWJ, the CBS Radio affiliate in Detroit. One day while doing a United Way promotional piece at the University of Michigan…