cystic fibrosis

November 25, 2020November 25, 2020

CFF Awards $3.3M to Advance Inhaled Antibiotic for Resistant P. aeruginosa Infections

cystic fibrosis, News

The Cystic Fibrosis Foundation (CFF) has awarded up to $3.3 million to Polyphor AG to advance the testing of an inhaled version of murepavadin, an antibiotic that targets multi-drug ... Read more

November 24, 2020November 24, 2020

CFF Awards Up to $3.75M to Develop Oral Antibiotic for NTM Infections

cystic fibrosis, News

The Cystic Fibrosis Foundation (CFF) awarded up to $3.75 million to Matinas BioPharma to support preclinical studies of MAT2501, a potential oral antibiotic to treat nontuberculous mycobacterium (NTM) infections in people ... Read more

November 19, 2020November 19, 2020

Trial of MS1819, Pancreatic Enzyme Therapy, May Add New Patient Arm

cystic fibrosis, News

AzurRx BioPharma is requesting a new patient arm be added to its ongoing Phase 2b trial investigating MS1819 capsules as a treatment for exocrine pancreatic insufficiency (EPI) in people with cystic fibrosis (CF). ... Read more

November 18, 2020November 19, 2020

A. fumigatus Lung Infections Linked to Age, Long-term Antibiotic Use

cystic fibrosis, News

Adult age up to 50 and chronic antibiotic use seem to be the greatest risk factors for lung infection by the fungus Aspergillus fumigatus among cystic fibrosis (CF) patients, ... Read more

November 17, 2020November 17, 2020

Pegylation Provides Long‐acting Version of Dornase Alfa for CF Treatment

cystic fibrosis, News

A modified version of Pulmozyme (dornase alfa), a widely-used cystic fibrosis (CF) therapy, lasts longer and reduces the need for treatment from once a day to once a week, ... Read more

November 13, 2020November 13, 2020

Trikafta Soon Be Up for Approval, Cystic Fibrosis Canada Reporting

cystic fibrosis, News

Following yearlong advocacy efforts, the triple-combination therapy Trikafta is expected to soon come up for approval before Health Canada, the country’s health regulatory agency, the non-profit patient group Cystic Fibrosis Canada has announced on its ... Read more

November 12, 2020November 12, 2020

KB407 Seen in Animal Studies to Safely Deliver Gene That Might Treat CF

cystic fibrosis, News

New findings from animal studies support the safety and effectiveness of KB407, a potential inhaled gene therapy for cystic fibrosis, its developer, Krystal Biotech, announced. Preclinical work is ongoing, and the therapy is ... Read more

November 11, 2020November 11, 2020

Phase 1/2 Trial of MRT5005, Potential Treatment for All With CF, Resumes in US

cystic fibrosis, News

Patient enrollment and dosing has resumed in a Phase 1/2 clinical trial testing MRT5005, Translate Bio‘s potential messenger RNA (mRNA) therapy for people with cystic fibrosis (CF) regardless of their underlying mutation. The trial, ... Read more

November 10, 2020November 10, 2020

Home Monitoring of Lung Health Possible With NuvoAir System, Studies Report

cystic fibrosis, News

The NuvoAir Home platform — NuvoAir’s respiratory support system for people with lung diseases — allows adults and children with cystic fibrosis (CF) to gather high quality data on ... Read more

November 9, 2020November 9, 2020

CFF Awards $2.4M to Advance CB-280 in Preventing Lung Infections

cystic fibrosis, News

The Cystic Fibrosis Foundation (CFF) has awarded up to $2.4 million to Calithera Biosciences to advance in testing CB-280, its investigative oral therapy that aiming to lower the risk of lung ... Read more