cystic fibrosis

May 18, 2020May 18, 2020

Antibiotic-resistant S. Maltophilia Spread Worldwide, Carry Diverse Genes, Study Reports

cystic fibrosis, News

The antibiotic-resistant bacterium Stenotrophomonas maltophilia, a dangerous bacteria for people with lung diseases such as cystic fibrosis (CF), is widely spread around the world, with most strains carrying virulence ... Read more

May 15, 2020May 15, 2020

How Trefoil Proteins Act to Thicken Mucus Detailed in Study

cystic fibrosis, News

Researchers identified a biochemical mechanism that regulates the thickness of mucus, and could serve as a target of new treatments for chronic respiratory illnesses that include cystic fibrosis (CF). The study, ... Read more

May 14, 2020May 14, 2020

CF Awareness Month Activities Varied, But Virtual, This Year

cystic fibrosis, News

While the COVID-19 outbreak has turned Cystic Fibrosis Foundation (CFF) activities into online events, Cystic Fibrosis Awareness Month continues to move forward, and with an emphasis on patient stories and education. ... Read more

May 13, 2020May 13, 2020

Phase 1b Study of CB-280 for CF Chronic Lung Infections May Open by September

cystic fibrosis

Calithera Biosciences announced plans to open by September a first clinical study of its oral investigational therapy CB-280 in people with cystic fibrosis (CF). The Phase 1b, dose-escalating trial (NCT04279769) in ... Read more

May 12, 2020May 12, 2020

Gene Therapy, KB407, Seen to Restore CFTR Protein in Cell Studies

cystic fibrosis, News

A potential gene therapy for cystic fibrosis, KB407, is able to induce the expression of normal CFTR protein in cell models of CF, its developer, Krystal Biotech, reports. These ... Read more

May 11, 2020May 11, 2020

Researchers Develop Promising Antibiotic Molecule for Drug-resistant Lung Infections

cystic fibrosis, News

A man-made antibiotic able to fight drug-resistant bacteria in the lungs with minimal toxicity to a person’s cells may be a promising approach to eliminate lung infections, such as ... Read more

May 8, 2020May 8, 2020

Trikafta Very Effective CF Therapy, But Still Too Costly, ICER Reports

cystic fibrosis

The Institute for Clinical and Economic Review (ICER) granted the therapy Trikafta the highest evidence rating (an “A”) for the treatment of cystic fibrosis (CF) in patients with either two copies the ... Read more

May 7, 2020May 7, 2020

CF Foundation, Beam Partner to Offer Free Online Exercise Classes

cystic fibrosis, News

The Cystic Fibrosis Foundation (CFF) is sponsoring free access to Beam, an online exercise platform that provides a variety of live and on-demand classes tailored for people with cystic fibrosis (CF), ... Read more

May 6, 2020May 6, 2020

AzurRx BioPharma Will Conduct Phase 2b Trial of MS1819 at TDN Clinical Sites

cystic fibrosis

AzurRx BioPharma has been authorized to conduct its Phase 2b OPTION 2 clinical trial evaluating MS1819, its investigative therapy for exocrine pancreatic insufficiency (EPI) associated with cystic fibrosis (CF), at ... Read more

May 5, 2020May 5, 2020

COVID-19 Outcomes in CF Patients Similar to General Public, Study Suggests

cystic fibrosis, News

People with cystic fibrosis (CF) infected with the new coronavirus appear to have better outcomes than initially anticipated, with their COVID-19 disease following a course similar to that of ... Read more