cystic fibrosis

August 13, 2018August 14, 2018

Airway Clearance Vests Fail to Show Measurable Lung Benefits in Short Term, Study Reports

cystic fibrosis, News

A clinical study into high-frequency chest wall oscillation vests — assessing their short-term impact on standard measures of lung function before and during use — challenges the view that these devices ... Read more

August 10, 2018August 10, 2018

Synspira’s SNSP113 Shows Ability to Completely Kill Drug-Resistant Bacteria in Lab, Study Reports

cystic fibrosis, News

The active ingredient of Synspira’s SNSP113, an inhaled investigational treatment for chronic lung infections, demonstrated an ability to completely eliminate antibiotic-resistant Pseudomonas aeruginosa bacteria, a major cause of lung ... Read more

August 9, 2018August 9, 2018

European Partners Combining Efforts to Develop New Gene Therapy for Cystic Fibrosis

cystic fibrosis

Pharmaceutical companies Boehringer Ingelheim and Oxford BioMedica are teaming up with the U.K. Cystic Fibrosis Gene Therapy Consortium (GTC) and Imperial Innovations in a collaborative effort to develop a first-in-class, long-term gene therapy to ... Read more

August 8, 2018August 8, 2018

Orkambi Approved by FDA as First CF Medicine for Children Ages 2-5

cystic fibrosis, News

Vertex Pharmaceuticals’ Orkambi (lumacaftor/ivacaftor), a licensed medicine used to treat cystic fibrosis (CF) patients ages 6 and older, has now been approved by the U.S. Food and Drug Administration ... Read more

August 7, 2018August 7, 2018

HeadsUp, a Urine-Based Diagnostic Test for CF Patients, Will be Tested in Phase 1/2 Trial

cystic fibrosis, News

Mologic, an U.K.-based company developing personalized diagnostic devices, announced the beginning of a Phase 1/2 clinical trial to test its urine-based diagnostic tool, HeadsUp, to monitor pulmonary exacerbations in patients ... Read more

August 6, 2018August 6, 2018

Acebilustat Seen to Prevent Pulmonary Exacerbations in CF Patients in Phase 2b Trial

cystic fibrosis, News

Topline data from a Phase 2b trial showed that the investigative therapy acebilustat taken once daily can reduce the number and frequency of pulmonary exacerbations in patients with cystic fibrosis (CF). ... Read more

August 3, 2018August 3, 2018

New, Rare Cell Type in Lung Airways Identified as Key Carrier of CFTR Gene, Study Reports

cystic fibrosis, News

A previously undiscovered and rare type of cell has been identified in the tissue lining the airway of the lungs and carrying high levels of the CFTR gene, the mutation ... Read more

August 2, 2018August 2, 2018

PERT Dose Affects Weight Gain in Infants with Cystic Fibrosis, Study Finds

cystic fibrosis, News

Cystic fibrosis is (CF) patients receiving higher doses of pancreatic enzyme replacement therapy (PERT) gain more weight, a recent report shows. PERT is a tablet that contains pancreatic enzymes. When ... Read more

August 1, 2018August 1, 2018

Specific Gene Mutation Causes Severe CF in Georgian Jewish Patients, Study Reports

cystic fibrosis, News

The Q359K/T360K gene mutation, which is commonly found in Jewish patients of Georgian descent, is associated with a particularly severe cystic fibrosis (CF) phenotype, according to researchers. Their study, ... Read more

July 31, 2018July 31, 2018

Disease Worsening, High Healthcare Costs Seen in CF Patients Insured by Medicaid

cystic fibrosis, News

A high number of sudden disease worsening episodes — pulmonary exacerbations — and associated increases in healthcare costs were observed in Medicaid patients with cystic fibrosis (CF), according to ... Read more

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