cystic fibrosis

October 14, 2020October 14, 2020

Toronto Scientist Wins Award for Work Into Alternative Way of Treating CF

cystic fibrosis, News

Medicine by Design, which supports work in regenerative medicines, gave a 2020 New Ideas Awards to support a researcher exploring an alternative pathway to the CFTR protein as a ... Read more

October 13, 2020October 13, 2020

Trial of Oral CB-280 for Chronic Lung Infections in CF Enrolling Across US

cystic fibrosis, News

A Phase 1b clinical trial evaluating Calithera Biosciences’ investigational oral therapy CB-280 is recruiting adults with cystic fibrosis (CF) and chronic airway infections at several U.S. sites. The trial’s ... Read more

October 12, 2020October 12, 2020

Certain Factors Could Predict Severe Episodes of Coughing Up Blood in CF Patients, Study Says

cystic fibrosis, News

Factors such as diabetes, a specific type of fungal infection, and previous mild to moderate episodes of hemoptysis, or coughing up blood, may help predict the risk of massive ... Read more

October 9, 2020October 9, 2020

Roche Acquires TMEM16A Portfolio for CF Treatment

cystic fibrosis, News

Roche has acquired Enterprise Therapeutics’s TMEM16A potentiator portfolio, which includes ETD002, a therapeutic candidate being evaluated in Phase 1 clinical trials for the treatment of cystic fibrosis (CF). The ... Read more

October 8, 2020October 9, 2020

Tobacco Smoke Exposure Limits Symdeko Benefit in Pediatric CF Patients

cystic fibrosis, News

Exposure to tobacco smoke limits the medicinal benefit of Symdeko (tezacaftor/ivacaftor combo) in young patients with cystic fibrosis (CF), according to a recent study. This finding suggests that smoking ... Read more

October 7, 2020October 7, 2020

Lenabasum Fails to Lessen Exacerbations in CF Patients in Phase 2 Trial

cystic fibrosis, News

A Phase 2 clinical trial of oral lenabasum in people with cystic fibrosis (CF) failed to meet its primary goal of reducing pulmonary exacerbations, the investigational therapy’s developer, Corbus Pharmaceuticals, announced. “We are very ... Read more

October 6, 2020October 6, 2020

Twincer Inhaler May Be Better Alternative to Nebulizers for Colistin Treatment

cystic fibrosis, News

Twincer, a dry powder inhaler (DPI), was shown to be a more attractive approach for the inhalation of colistin — an antibiotic used to treat lung infections in people with ... Read more

October 2, 2020October 2, 2020

NTM Infection Rate in Young CF Patients in UK Remains Stable But High, Study Finds

cystic fibrosis, News

The frequency of nontuberculous mycobacteria (NTM) infections in children and adolescents with cystic fibrosis (CF) in the U.K. remained stable from 2016 to 2018, but substantially higher than at ... Read more

October 1, 2020October 1, 2020

Study Compares Oral and Intravenous Antibiotics for P. aeruginosa Infections in People With CF

cystic fibrosis, News

Oral antibiotics are just as effective as intravenous (into-the-vein) antibiotics at killing Pseudomonas aeruginosa bacteria in people with cystic fibrosis (CF), a new study shows. This finding may allow ... Read more

September 30, 2020September 30, 2020

Study: Screening for Hearing Loss in CF Patients Feasible With Tablet-based Tests

cystic fibrosis, News

Tablet-based hearing tests can accurately screen for hearing loss in people with chronic lung diseases such as cystic fibrosis (CF) without specialist supervision, according to a recent study. This ... Read more